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DNA穿越纳米孔的力学研究 被引量:1

Mechanical Study on Translocation of DNA Through a Solid Nanopore
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摘要 控制DNA穿越纳米孔的速度对于低成本基因测序起着重要作用.为此,用流体力学研究DNA穿越纳米孔的过程,提出了控制DNA穿越速度的方法. Driving DNA through a synthetic solid nanopore is potentially a low-cost sequencing method. To achieve a single base-pair resolution, DNA's translocation velocity has to be controlled. I use a theoretical model to investigate the process of DNA translocation in a nanopore. Based on derived results, several methods to control the DNA translocation speed are suggested.
作者 朱红
出处 《喀什师范学院学报》 2008年第6期43-44,共2页 Journal of Kashgar Teachers College
关键词 流体力学 DNA 纳米孔 雷诺数 Sequencing DNA Nanopore Fluid dynamics
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参考文献2

  • 1lqbal S M, Akin D, Bashir R. Solid-state nanopore channels with DNA selectivity [J ]. Nature: Nanotechnology, 2007:2:243-248.
  • 2Landau L D,Lifshitz E M. Fluid dynamics [M]. Pergamon Press, 1987.

同被引文献3

  • 1BINQUAN L. Electro-osmotic screening of the DNA charge in a nanopore[J]. Phys Rev E, 2008,78(2):021 912.
  • 2DORP S. Origin of the electrophoretic force on DNA in solid-state nanopores[J].Nature Physics, 2009(5) :347-351.
  • 3DING K J. Dependence of zeta potential on polyelectrolyte moving through a solid-state nanopore[J]. Applied Physics Letters, 2009,94(1) :014 101.

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