摘要
在UV/H2O2光催化体系中,通过高级氧化法在NiTi SMA表面生成贫Ni的Ti氧化膜。通过亲水性试验、血小板黏附试验以及MTT细胞毒性试验对改性后试样的生物相容性进行了系统的评价,研究发现改性后试样的亲水性得到明显改善。表面血小板黏附数量减少,变形和团聚现象得到抑制,形成血栓的可能性降低,血液相容性得到提高。改性后试样的细胞相对增殖率(RGR)高于化学抛光的试样,试样周围细胞分裂增生良好,与材料边缘结合自然,改性处理同样提高了试样的细胞相容性。结果表明光催化高级氧化是提高NiTiSMA生物相容性的一种有效方法。
Advanced oxidation in gv/n2O_(2)photocatalytic system could results in the formation of a titanium oxides film depleted of Ni on NiTi shape memory alloy(SMA).In this work,the biocompatibility of advanced oxidized NiTi SMA was systematically investigated by contact angle test,platelet adhesive test and MTT cytotoxicity test.It was found that the wettability of NiTi SMA could be improved by photocatalytic oxidation.The number of platelets on surface modified NiTi SMA was decreased and moreover the phenomena of distortion and congregativeness of platelets were controlled,thus the possibility of thrombas formation was depressed.As a result,the hemocompatibility of NiTi SMA was improved.The relative growth rate(RGR)of fibroblasts of the modified NiTi SMA was higher than that for the chemically polished one.The cell proliferation in the vicinity of the modified NiTi SMA was well and the cells combined with the sample naturally.All those suggest that the cytocompatibility of the surface modified NiTi SMA was improved too.The results indicate that advanced oxidation in UV/H2O_(2)photocatalytic system is a promising way to improve the biocompatibility ofNiTi SMA.
作者
王如萌
储成林
李艳芬
尹立红
浦跃朴
董寅生
林萍华
朱剑豪
Wang Rumeng;Chu Chengin;Li Yanfen;Yin Lihong;Pu Yaopu;Dong Yinsheng;Lin Pinghua;Paul K.Chu(School of Material Science&Engineering,Southeast University,Nanjing 211189,China;City University of Hongkong,Hongkong,China)
出处
《稀有金属材料与工程》
SCIE
EI
CAS
CSCD
北大核心
2008年第11期2027-2030,共4页
Rare Metal Materials and Engineering
基金
国家自然科学基金(50501007)
教育部新世纪优秀人才支持计划资助
江苏省自然科学基金(BK2007515)
