摘要
建立了用紫外分光光度法测定注射用硫酸普拉睾酮钠含量的方法。以蒸馏水为溶剂,在波长288nm下用紫外分光光度法测定,在2～10mg/mL浓度范围内注射用硫酸普拉睾酮钠含量与吸光度呈良好线性关系,平均回收率为99.2%,RSD为1.6%,稳定性强,吸光度在8h内无明显变化。结果表明,该方法简单方便.准确度和精密度均能满足分析要求,可用于注射用硫酸普拉睾酮钠的质量控制及生产中间体的质量控制。
The sodium prasterone sulfate was dissolved with pure water and determined by UV spectrophotometry at 289nm. There was a good linear relationship in the range of 2-10mg/L. The recovery was 99.2% and the RSD was 1.6%. The results were stable and no obvious change of absorbance was observed in 8 hours. The accuracy and precision can meet the analytical requirement. The method is simple and convenient and can be used for quality control of sodium prosteron sulfate injection and medial products.
出处
《分析仪器》
CAS
2008年第6期34-36,共3页
Analytical Instrumentation
