摘要
从中国南海海绵Pachychalina sp.正丁醇可溶部分获得了5个化合物,通过UV,IR,~1H-NMR,^(13)C-NMR,MS,~1H-~1HDQFCOSY等实验确定了它们的结构分别是:对羟基苯醋酸甲酯(1),胸腺嘧啶(2),尿嘧啶(3),胸腺嘧啶脱氧核苷(4)和尿嘧啶脱氧核苷(5)。其中化合物(1)是首次从我国南海海洋生物中获得;化合物(5)则是首次从海绵中分离得到的天然产物。
Five known compounds were isolated from the marine sponge Pachychalina sp. of South China Sea. The crud ethanol extract was partitioned between ethyl acetate and water,then between n- butanol and water. The butanol fraction was chromatographed on silica gel column to obtain Methyl p-hydroxyphenylacetate (1) , thymine (2) , uracil (3 ) , thymidine (4 ) and 2'-deoxyurdine (5). Their structures were determined by UV, IR,MS,1H-NMR,13C-NMR and H-1HDQFCOSY data. It is first reported compound(1) isolated from Chinese marine organisms,and Compoud(5) isolated from marine sponge.
出处
《天然产物研究与开发》
CAS
CSCD
1997年第3期1-4,共4页
Natural Product Research and Development
基金
国家自然科学基金
中科院上海有机化学研究所生命有机国家重点实验室资助
关键词
海绵
化学成分
分离
提纯
结构鉴定
marine sponge,chemical constituent,isolation,structure determination
