期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

腹膜透析对尿毒症大鼠腹膜电荷屏障变化的影响 被引量：1

原文传递
导出
摘要 腹膜透析是尿毒症的一种肾脏替代治疗方式。透析过程中蛋白质丢失是造成蛋白质营养不良的一个重要原因．文献报道每天自透析液中丢失的蛋白质多达10．5g左右，其中白蛋白占49％。一般认为通透性增加是蛋白质丢失的主要原因。目前发现腹膜也具有分子屏障以及电荷屏障，但尿毒症以及腹膜透析是否会影响电荷屏障以及蛋白质的漏出，目前均未明确，本研究对此进行了探讨。
作者 俞国庆 文文 陈祖医 高升 陈建 庄永泽
机构地区 南京军区福州总医院肾内科 南京军区福州总医院呼吸内科
出处 《中华肾脏病杂志》 CAS CSCD 北大核心 2008年第11期847-848,共2页 Chinese Journal of Nephrology
基金 福建省科技厅青年创新基金资助（2004J068）
关键词 腹膜透析 电荷屏障 尿毒症 蛋白质营养不良 蛋白质丢失 大鼠 治疗方式 透析过程
分类号 R692.5 [医药卫生—泌尿科学]
  • 相关文献

参考文献5

  • 1Yeun JK, Kaysen GA. Factors inflenceing serum albumin in dialysis patients. Am J Kidney Dis, 1998, 32 (6 Suppl 4): S118-S125.
  • 2Lyepoldt JK, Enderson LW. Molecular charge influences transperitoneal macromolecule transport. Kidney Int, 1993, 43: 837-844.
  • 3袁江姿,钱家麒,方炜,戴慧莉.尿毒症腹透对大鼠腹膜形态和功能的影响[J].上海交通大学学报（医学版）,2007,27(10):1189-1192. 被引量：5
  • 4O'Donnell MD, FitzGerald O, MeGeeney KF. Differential serum amylase determination by use of an inhibitor, and design of a routine procedure. Clin Chem, 1977, 23: 560- 566.
  • 5Buis B, Koomen GC, hnholz AL, et al. Effect of electric charge on the transperitoneal transport of plasma proteins during CAPD. Nephrol Dial Transplant, 1996, 11: 1113- 1120.

二级参考文献20

  • 1Stigant CE, Bargman JM. What's new in peritoneal dialysis: biocompatibility and continuous flow peritoneal dialysis[ J]. Curr Opin Nephrol Hypertens, 2002,11 (6) :597 - 602.
  • 2Lopez-Cabrera M, Aguilera A, Aroeira LS, et al. Ex vivo analysis of dialysis effluent-derived mesothelial cells as an approach to unveiling the mechanism of peritoneal membrane failure [ J ]. Perit Dial Int, 2006,26( 1 ) :26 - 34.
  • 3Comber S, Miyata T, Moulin P, et al. Vascular proliferation and enhanced expression of endothelial nitric oxide synthase in human peritoneum exposed to long-term peritoneal dialysis[ J]. J Am Soc Nephro1,2000,11 (4) : 717 - 728.
  • 4Margetts PJ, Gyorffy S, Kolb M, et al. Antiangiogenic and antifibrotic gene therapy in a chronic infusion model of peritoneal dialysis in rats[J]. JAmSocNephrol, 2002,13(3) :721 -728.
  • 5Davies SJ, Phillips L, Griffiths AM, et al. What really happens to people on long-term peritoneal dialysis [ J] ? Kidney Int, 1998,54 (6) :2207 -2217.
  • 6Musi B, Braide M, Carlsson O, et al. Biocompatibility of peritoneal dialysis fluids: long-term exposure of nonuremic rats[ J]. Perit Dial Int,2004,24( 1 ) :37 -47.
  • 7Mortier S, Faict D, Schalkwijk CG, et al. Long-term exposure to new peritoneal dialysis solutions: Effects on the peritoneal membrane [ J]. Kidney Int,2004,66( 3 ) : 1257 - 1265.
  • 8Churchill DN, Thorpe KE, Nolph KD, et al. Increased peritoneal membrane transport is associated with decreased patient and technique survival for continuous peritoneal dialysis patients. The Canada-USA (CANUSA) Peritoneal Dialysis Study Group[ J]. J Am Soc Nephrol, 1998,9 ( 7 ) : 1285 - 1292.
  • 9Comber S, Ferrier ML, Van Landschoot M. Chronic uremia induces permeability changes, increased nitric oxide synthase expression, and structural modifications in the peritoneum [ J]. J Am Soc Nephrol,2001,12 (10) :2146 - 2157.
  • 10Krediet RT, Lindholm B, Rippe B. Pathophysiology of peritoneal membrane failure[J]. Petit Dial Int, 2000,20 ( Suppl 4) :S22 - S42.

共引文献4

同被引文献10

  • 1袁江姿,钱家麒,方炜,戴慧莉.尿毒症腹透对大鼠腹膜形态和功能的影响[J].上海交通大学学报（医学版）,2007,27(10):1189-1192. 被引量：5
  • 2Lyepoldt JK,Henderson LW. Molecular change influences transperitoneal macromolecule transport[J].Kidney International,1993,(04):837-844.
  • 3Kborana AA,Sahni A,Ahland OD. Heparin inhibition of endothelial cell proliferation and organization is dependent on molecular weight[J].Arteriosclerosis,Thrombosis,and Vascular Biology,2003,(11):2110-2115.
  • 4Schilte MN,Loureiro J,Keuning ED. Long-term intervention with heparins in a rat model of peritoneal dialysis[J].Peritoneal Dialysis International,2009,(01):26-35.
  • 5O'Donnell MD,FitzGerald O,McGeeney KF. Differential serum amylase determination by use of an inhibitor,and design of a routine procedure[J].Clinical Chemistry,1977,(03):560-566.
  • 6Fox JG,Quin JD,O Rcilly DS. Assessment of glomerularcharge selectivity in man by differential clearance of isoamylases[J].Clinical Science(London),1993,(04):449-454.
  • 7Thum CN,Oelbaum RS,Foo AY. Renal isoamylase clearance as a measurement of altered renal charge selectivity in patients with diabetes mellitus[J].Annals of Clinical Biochemistry,1993,(PT 5):449-453.
  • 8Buis B,Koomen GC,Imholz AL. Effect of electric charge on the transperitoneal transport of plasma proteins during CAPD[J].Nephrology Dialysis Transplantation,1996,(06):1113-1120.
  • 9俞国庆,陈建,庄永泽,张明炜.持续非卧床腹膜透析与蛋白质营养不良的相关因素分析[J].临床肾脏病杂志,2008,8(5):221-222. 被引量：5
  • 10俞国庆,文文,陈建,庄永泽,林沁,彭卫华,王丽萍.腹膜透析患者腹膜电荷屏障对透析液蛋白质丢失的影响[J].肾脏病与透析肾移植杂志,2008,17(4):335-338. 被引量：2

引证文献1

中华肾脏病杂志
2008年 第11期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部