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小胶质细胞在肌萎缩侧索硬化症研究中的作用 被引量：1

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摘要 肌萎缩侧索硬化症(ALS)是以选择性运动神经元变性丢失、进行性瘫痪为特征的慢性退行性疾病,其相关发病机制学说众多,目前尚不明确。近年研究认为,运动神经元与其周围小胶质细胞的相互作用异常参与了ALS发病及病情进展,且小胶质细胞激活参与炎症反应在ALS发病中的作用越来越受到关注。此文就ALS发病中小胶质细胞的激活、作用以及可能作用机制做一综述,通过对小胶质细胞的调控可能为ALS治疗提供新的希望。
作者 刘桂冬 肖勤 陈生弟
机构地区 上海交通大学医学院附属瑞金医院神经科上海交通大学医学院神经病学研究所
出处 《中国神经免疫学和神经病学杂志》 CAS 2008年第6期461-462,466,共3页 Chinese Journal of Neuroimmunology and Neurology
关键词 肌萎缩侧索硬化症 小胶质细胞 运动神经元 慢性退行性疾病
分类号 R744.8 [医药卫生—神经病学与精神病学]
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参考文献9

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同被引文献12

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中国神经免疫学和神经病学杂志
2008年 第6期

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