摘要
本文对皮肤β-AP蛋白进行光镜免疫组比研究。AD组8例;MID组8例;NDC组24例。结果显示:所有病例的皮肤角质层和毛囊以及部分汗腺、皮脂腺和血管有阳性免疫反应。3组间比较在角质层、毛囊、汗腺及皮脂腺阳性着色反应无显著差异,而皮肤血管阳性反应呈现AD>MID>NDC趋势,提示β-AP在皮肤血管的阳性免疫反应可能对AD诊断有意义。
Light microscopy immunohistochemistry were performed to study skin tissues β-Ap. The cases were divided into three groups: Eight cases with AD; Eight cases with MID and twenty-four cases with non-dementia controls. The results showed clearly immunoreaction on horny layer and hair follicles of skin tissues in all three groups, and vessels, sweat and sebaceous glands in parts of the specimens of each group. There is no significant difference between each of the group in horny layer, hair follicles, sweat and sebaceous glands staining. There is a tendancy of AD>MID>NDC. These findings suggest that β-AP immunoreaction in skin vessels might be a significant marker of the AD.
出处
《临床神经科学》
1997年第1期25-27,共3页
Chinese Journal of Clinical Neurosciences
基金
卫生部研究基金