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外周造血干/祖细胞采集52例次临床观察 被引量:3

Clinical Observation of 52 Peripheral Blood Stem/Progenitor Cells Harvesting
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摘要 目的:观测外周造血干/祖细胞采集术对造血干/祖细胞采集的临床效果。方法:对14例患者及11例健康捐献者进行外周造血干/祖细胞采集术52例次,观测采集前后外周血WBC、RBC、Hb、Hct、Plt,采集后CD34+细胞、CFU-GM量,以及不良反应。结果:经过1~3次采集,采集量达到造血干/祖细胞移植所需量,不良反应轻微。结论:外周血干/祖细胞采集具有处理量大,副作用小,安全高效等优点。 Objective:To observe the clinical effect of peripheral blood stem/progenitor cells harvesting.Methods:Harvesting 52 times of peripheral blood stem/progenitor cells from 14 patients and 11 healthy donors,and observing peripheral WBC,RBC,Hb,Hct,Plt CD34+ cells,CFU-GM and adverse reaction.Results:The amount of stem/progenitor cells consistent with the need of transplantation,and adverse reaction is little.Conclusion:Peripheral blood stem/progenitor cells harvesting is a safe method,circulation volume is large and adverse reaction is little.
出处 《华西医学》 CAS 2008年第1期50-51,共2页 West China Medical Journal
关键词 血细胞单采术 造血干/祖细胞 临床应用 hemapheresis,stem/progenitor cell,clinical application
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  • 1[1]Hillyer CD,Tiegerman KO,Berkman EM.A commercially available culture medium compares favorably to laboratory medium(LM)for assay of peripheral blood colony forming units(CFU).Bone Marrow Transplant,1991,7(6):493
  • 2[2]Price TH.Leukapheresis and stem cell harvest.In:Rossi EC,Simon TL,Moss GS,et al.Principles of transfusion medicine.2nded,William & Wilkins,1996,551~555

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