摘要
目的:考察常温下保存(茅)苍术挥发油主要化学成分的稳定性,并初步比较不同时间常温下保存挥发油的抗炎作用。方法:用气-质联用仪分离、分析、鉴定苍术挥发油的主要化学成分,以紫外可见分光光度计比较室温下保存的挥发油颜色随时间变化,并以二甲苯致炎法初步探讨挥发油不稳定性对抗炎作用的影响。结果:以气-质联用仪分析鉴定出挥发油中的17种成分,其中相对百分含量≥4%的主要成分为β-芹子烯、茅术醇、β-桉叶醇、α-红没药醇和一个未知成分。室温下保存(茅)苍术挥发油由原来的淡黄色逐渐变为无色,彼此之间发生成分转化。常温下保存时间越长,其抗急性炎症作用增强。结论:(茅)苍术挥发油常温下保存具有不稳定性;随保存时间延长,其抗炎作用增强。
Objective：To analyze instability of the chemical constituents of volatile oil in Rhizome Atractrylodis and to preliminarily study its anti - inflammation effects in different storage period. Method ： The constituents of volatile oil in Rhizome Atraetrylodis were separated and identified by GC/MS, and subsequent color change with time under room temperature w＇as investigated by UV/spectrometer. The effects of the instability on the anti-inflananation action were also investigated with dimethylbenzene - induced model of mice. Results： 17 compounds were isolated and identified, among them,β-selinene,hinesol, β-eudesmol, α- bisabolol,and an unknown compound are main components with relative percentage not less than 4%. Under room temperature, the volatile oil color changed from light yellow to achromatism and the constituents transform into each other. The anti - inflammation effects enhanced with longer storage period under room temperature. Conclusion ： Under room temperature, the storage of volatile oil in Rhizome Atractrylodis is instable and the longer of the storage period the more positive of the anti - inflammation effects.
出处
《辽宁中医杂志》
CAS
北大核心
2008年第11期1733-1734,共2页
Liaoning Journal of Traditional Chinese Medicine
基金
广州中医药大学创新基金(98047)
关键词
苍术
挥发油
气/质联用仪
不稳定性
抗炎作用
Volatile oil
Rhizome Atractrylodis
GC/MS
Instability
Anti - inflammation effect
