摘要
目的:观察肺岩宁方对晚期非小细胞肺癌患者血清CEA、CYFRA21-1水平,免疫功能以及中医证候的影响。方法:50例确诊为Ⅲa、Ⅲb、Ⅳ期非小细胞肺癌患者,中医辨证为精气亏虚型,中药肺岩宁方治疗2个月。结果:肺岩宁方可以降低血清CEA和CYFRA21-1水平,提高晚期非小细胞肺癌患者CD3、CD4、CD4/CD8细胞水平,降低CD8细胞水平。患者神疲乏力、动则气喘、腰膝酸痛、少气懒言等症状明显改善,卡氏评分上升6.06。结论:肺岩宁方具有明显改善晚期肺癌患者的生活质量,显著提高患者的免疫功能的作用。
Objective ：The purpose of this study is to observe the influence of CEA, CYFRA21-1 and immunological function in advanced non-small-cell lung cancer patients by intervention of Feiyanning Formula. Method：50 patients diagnosed of non - small - cell lung cancer of Ⅲa, Ⅲb, Ⅳ stage, differentiated by TCM of deficiency of vigour and qi were treated by Feiyanning Formula for 2 month. Observe the influence of CEA, CYFRA21- 1 ,immunological function and syndrome of TCM. Result：Downregulation of CEA, CYFRA21-1, CD8 and upregulation of CD3, CD4, CD4/CD8 of non - small - cell lung cancer patients were observed. Syndrome of debilitation, soreness of loin and lap, deficiency of qi were improved obviously. KPS rised 6.06. Conclusion ： The traditional Chinese medicine Feiyanning has a significant effect on improvement of the quality of life and immunological function of advanced lung cancer.
出处
《辽宁中医杂志》
CAS
北大核心
2008年第11期1707-1708,共2页
Liaoning Journal of Traditional Chinese Medicine
基金
上海市重点学科建设项目资助(Y0302)
