摘要
为探讨骨髓活检在小儿再生障碍性贫血（简称再障）临床应用的价值，采用骨髓活检改良制片法对88例再障患儿进行骨髓组织学定量分析并与涂片对照；同时对其中30例进行治疗后观察；并对76例进行随访。结果表明：小儿再障诊断符合率和疗效判定骨髓活检高于涂片检查，疗效与骨髓造血组织容量，造血细胞绝对值呈正相关，而与非造血细胞绝对值呈负相关；初检造血组织容量大小与生存期长短有关。结果提示：骨髓活检改良制片法适用于儿童，其可作为小儿再障早期诊断、疗效判定、预后评估的一个客观指标。
To investigate clinical application of bone marrow biopsy (BMB)with aplastic anemia(AA)in children. The BMB were analyzed quantitatively by means of improved histoligicalysection technique in 88 cases with AA in children and compared with bone marrow smears,and 30 of them were observed after treatment. Of 76 cases were followed--up. The resultsshowed that BMB was higher in coincidence of diagnosis and evaluate of treatment effectthan that in marrow smears;There were significantly positive correlation between the treatment effect and the hematopoietic tissue account for percentage of marrow and the absolutecounts hetnatocyted,and negative correlation between the treatment effect and the absolutecounts no--hematocytes;The survival time related to the hematopoietic tissue account for percentage of marrow at initial examination. The results indicated that BMB of improved sectiontechique was suitable for children. It is useful as a objective standard in making early diagnosis,and evaluating treatment effect and prognosis with AA in children.
出处
《中国小儿血液》
1997年第2期66-69,共4页
China Child Blood
