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静脉复合麻醉对胆囊切除术患者血浆内皮素水平的影响

Investigation on the Level of Endothelin in patients with Cholecystectomy Performed with Intravenous Combined Anesthesia
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摘要 采用放免分析方法测定64例胆囊结石择期胆囊切除术患者静脉复合麻醉前后血浆内皮素水平变化,结果表明,静脉复合麻醉后患者收缩压(101.5±27.4mmHg)较麻醉前显著降低(P<0.05),血浆内皮素水平(162.4±31.8pg/ml)亦较麻醉前降低(P<0.05),表明静脉复合麻醉后,血浆内皮素的合成、分泌、抑制或代谢速率增加,致血浆内皮素水平降低是导致麻醉后血压下降的原因之一。 The plasma levels of endothelin pre and post intravenous combined anesthesia were detected in 64 cases of cholecystectomy patients by means of radioimmunoassay The results showed that systilic blood pressure(101 5±27 4mmHg)in the recovery period was decreased significantly( P <0 05) The plasma level of endothelin in the recovery period(162 4±31 8pg/ml)was decreased significantly ( P <0 05)as compared to the anesthesia stage The results suggested that reduction of blood pressure in the recovery period was due to inhibition of endothelin synthesis or to the increased metabolism rate
出处 《中国中西医结合外科杂志》 CAS 1997年第5期340-341,共2页 Chinese Journal of Surgery of Integrated Traditional and Western Medicine
关键词 内皮素 胆囊切除术 静脉麻醉 endothelin,anesthesia,surgical operation,radioimmunoassay
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