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金银花当归配伍对实验性腹主动脉瘤大鼠血清中炎症介质的影响及其意义 被引量:6

Angelica Honeysuckle Combination of Experimental Abdominal Aortic Aneurysm in Serum Inflammatory Mediators and its Significance
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摘要 应用金银花与当归配伍,股主动脉瘤大鼠血清中炎性介质CRP和TNF-α的含量明显下降,动脉壁炎性细胞的浸润程度明显减轻,同时减轻了腹主动脉局部的扩张,其作用优于两种中药的单独应用。指出:解毒活血中药能否减少动脉壁基质金属蛋白酶(MMPs)的释放量,尚须进一步的实验证实。 Angelica compatibility with honey suckle, shares aortic aneurysm serum inflammatory mediators in CRP and TNF- α levels decreased, inflammatory artery wall cells significantly reduce the level of infiltration and at the same time to reduce the abdominal aorta of the local Expansion of its role in traditional Chinese medicine is beter than two separate applications. Promoting blood circulation antidotes medicine can reduce arterial wall matrix metalloproteinases(MMPs) emissions, requires further experimental confirmation.
机构地区 辽宁中医药大学
出处 《实用中医内科杂志》 2008年第11期3-4,共2页 Journal of Practical Traditional Chinese Internal Medicine
基金 辽宁省教育厅课题(2004.F130)
关键词 炎性介质 C反应蛋白 肿瘤坏死因子 解毒活血法 实验性腹主动脉瘤 Inflammatory mediators C - reactive protein tumor necrosis factor activating blood de- toxification method experimental abdominal aortic aneurysm
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参考文献3

  • 1Johnston KW. Nonruptured abdominal aortic aneurysm:six - year follow- up results from the multicenter prospective Canadian aneurysm study[ J]. J Vasc Surg, 1994,20 : 163 - 170.
  • 2Kobayashi H, Matsushita M, Oda K, et al. Effects of atherosclerotic plaque on the enlargement of an experimental model of Abdominal Aortic Aneurysm in rabbits[ J]. Eur J Vasc EndoVase Surg,2004, 28 (1) :71 -78.
  • 3夏泉,张平,李绍平,王一涛.当归的药理作用研究进展[J].时珍国医国药,2004,15(3):164-166. 被引量:287

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