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阻塞性睡眠呼吸暂停低通气综合征患者下颌肌电活性的评价 被引量:1

Characteristic of mandibular muscle activity in patients with obstructive sleep hypopnea apnea syndrome
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摘要 目的探讨用于临床的下颌肌群肌电活性的评价指标。方法采用下颌肌肌电图检查与夜间多道睡眠监测(PSG)同步进行的方法,对确诊为阻塞性睡眠呼吸暂停低通气综合征(OSAHS)的50例男性患者进行监测。分析其中15例患者1周前后两次监测的下颌肌电活性比的重测信度;比较50例患者非快动眼睡眠期(NREM)与快动眼睡眠期(REM)下颌肌电活性比的差异,分析下颌肌电活性比与年龄、体质量指数(bodymassindex,BMI)、呼吸紊乱指数(apneahypopneaindex,AHI)、最低血氧饱和度的相关性。结果15例患者的前后两次监测的下颌肌电活性比的重测信度〉0.7。50例患者NREM期下颌肌电活性比平均(x±s,下同)为1.84±0.64,REM期为1.68±0.48,两者进行配对t检验,差异有统计学意义(t=2.849,P=0.006),NREM期大于REM期。运用Pearson相关分析法进行分析,肌电活性比与年龄、AHI以及REM期AHI呈负相关,相关系数依次为-0.336,-0.339,-0.338,P值均〈0.05,而与BMI、最低血氧饱和度无相关性。结论下颌肌电活性比是一个较稳定的指标,在一定程度上能够反应下颌肌肉的活性。 Objective To establish an index that can evaluate the genioglossus muscle activity and investigate the relationship between the genioglossus muscle activity and the severity of patients with obstructive sleep hypopnea apnea syndrome (OSAHS). Methods Mandibular muscle electromyography (EMG) and polysomnography (PSG) were used in fifty patients with OSAHS. The difference of mandibular muscle activity between the twice muscle activity of fifteen patients and between in non rapid eye movement (NREM) stage and rapid eye movement (REM) stage on fifty patients were analyzed. The relationship between the index and age, body mass index ( BMI), apnea hypopnea index ( AHI), and the lowest oxygen saturation was evaluated. Results There was no statistical difference between the twice muscle activtity in fifteen patients. The average index in NREM was 1.84 ± 0. 64 x± s, the same below), in REM was 1. 68 + 0. 48. The difference of mandibular muscle activity between in NREM stage and REM stage was significant(t = 2. 849, P 〈 0. 05 ). By pearson test there was relationship between the index and age and AHI, the correlation coefficient was - 0. 336, - 0. 339, - 0.338 and P 〈 0.05 . There was no relationship between the index and BMI and the lowest oxygen saturation. Conclusions This index that is stable can evaluate the mandibular muscle activity to some degree.
出处 《中华耳鼻咽喉头颈外科杂志》 CAS CSCD 北大核心 2008年第11期814-817,共4页 Chinese Journal of Otorhinolaryngology Head and Neck Surgery
关键词 睡眠呼吸暂停 阻塞性 腭肌 肌张力 肌电描记术 Sleep apnea, obstructive Palatal muscles Muscle tonus Electromyography
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参考文献7

  • 1Eikermann M, Vogt FM, Herbstreit F, et al. The predisposition to inspiratory upper airway collapse during partial neuromuscular blockade. Am J Respir Crit Care Med, 2007, 175 : 9-15.
  • 2Mezzanotte WS, Tangel DJ, White DP. Waking genioglossal electromyogram in sleep apnea patients versus normal controls ( a neuromuscular compensatory mechanism). J Clin Invest, 1992, 89: 1.571-1579.
  • 3陈丽艳,叶京英,崔吉亨.阻塞性睡眠呼吸暂停低通气综合征患者颏舌肌肌电活性分析[J].中国耳鼻咽喉头颈外科,2005,12(7):453-457. 被引量:11
  • 4Pierce R, White D, Malhotra A, et al. Upper airway collapsibility, dilator muscle activation and resistance in sleep apnoea. Eur Respir J, 2007, 30 : 345-353.
  • 5Lo YL, Jordan AS, Malhotra A, et al. Influence of wakefulness on pharyngeal airway muscle activity. Thorax, 2007, 62: 799-805.
  • 6Patil SP, Schneider H, Marx JJ, et al. Neuromechanical control of upper airway patency during sleep. J Appl Physiol, 2007, 102: 547-556.
  • 7Eikermann M, Jordan AS, Chamberlin NL, et al. The influence of aging on pharyngeal collapsibility during sleep. Chest, 2007, 131 : 1702-1709.

二级参考文献15

  • 1Hudgel DW.Mechanisms of obstructive sleep apnea. Chest,1992, 101: 541-549.
  • 2Brouillette RT, Thach BT.A neuromuscular mechanism maintaining extrathoracic airway patency. J Appl Physiol, 1979,46: 772-779.
  • 3Suratt PM, Mctier RF, Wilhoit SC. Upper Airway muscle activation:Is augmented in patients with obstructive sleep apnea compared with that in normal subjects. Am Rev Respir Dis, 1998, 137:889-894.
  • 4Sauerland EK, Sauerland BA, Orr WC, et al. Non-invasive electromyography of human genioglossal(tongue)activity.Electromyogr Clin Neurophysiol, 1981, 21: 279-286.
  • 5Doble EA,Leiter JC,Knuth SL,et al.A noninvasive intraoral electromyographic electrode for genioglossus muscle.J Appl Physiol, 1985, 58: 1378-1382.
  • 6Fogel RB,Malhotra A,Shea SA,et al. Reduced genioglossal activity with upper airway anesthesia in awake patients with OSA.JAppl Physiol, 2000, 88: 1346-1354.
  • 7van Lunteren E, Strohl KP.The muscles of the upper airways.Clin Chest Med, 1986, 7: 171-188.
  • 8Malhotra A, Pillar G, Fogel RB, et al.Genioglossal but not palatal muscle activity relates closely to pharyngeal pressure.Am JRespir Crit Care Med, 2000, 162 (3 Pt 1): 1058-1062.
  • 9Mezzanotte WS, Tangel DJ, White DP. Influence of sleep onset on upper-airway muscle activity in apnea patients versus normal controls.Am J Respir Crit Care Med, 1996, 153 (6Pt 1): 1880-1887.
  • 10Mezzanotte WS, Tangel DJ, White DP. Waking genioglossal electromyogram in sleep apnea patients versus normal controls (a neuromuscular compensotary mechanism). J Clin Invest,1992, 89: 1571-1579.

共引文献10

同被引文献19

  • 1叶京英,王小轶,韩德民,高莉敏.中老年女性阻塞性睡眠呼吸暂停低通气综合征的社区调查[J].中华耳鼻咽喉头颈外科杂志,2005,40(8):611-617. 被引量:40
  • 2Kim J, In K, Kim J, et al. Prevalence of sleep-disordered breathing in middle-aged Korean men and women. Am J Respir CritCareMed, 2004, 170: 1108-1113.
  • 3Yaggi HK, Concato J, Kernan WN, et al. Obstructive sleep apnea as a risk factor for stroke and death. N Engl J Med, 2005, 353: 2034-2041.
  • 4Jordan AS, Wellman A, Heinzer RC, et ai. Mechanisms used to restore ventilation after partial upper airway collapse during sleep in humans. Thorax, 2007, 62: 861-867.
  • 5Oliven A, Kaufman E, Kaynan R, et al. Mechanical parameters determining pharyngeal collapsibility in patients with sleep apnea. J Appl Physiol, 2010, 109: 1037-1044.
  • 6Li Y, Ye J, Li T, et al. Anatomic predictors of retropalatal mechanical loads in patients with obstructive sleep apnea. Respiration, 2011, 82: 246-253.
  • 7Wellman A, Edwards BA, Sands SA, et al. A simplified method for determining phenotypic traits in patients with obstructive sleep apnea. JAppl Physiol (1985) , 2013, 114: 911-922.
  • 8Eckert D J, White DP, Jordan AS, et aI.Defining phenotypic causes of obstructive sleep apnea. Identification of novel therapeutic targets. Am J Respir Crit Care Med, 2013, 188: 996-1004.
  • 9Newman AB, Foster G, Givelber R, et al. Progression and Regression of Sleep-Disordered Breathing with Changes in Weight. Arch Intern Med, 2005, 165: 2408-2413.
  • 10Polotsky M, Elsayed-Ahmed AS, Pichard L, et al. Effect of age and weight on upper airway function in a mouse model. J Appl Physiol, 2011, 111: 696-703.

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