摘要
目的:通过角膜缘上皮移植,改善化学伤与热烧伤穿透性角膜移植片的预后。方法:严重陈旧性眼化学伤与热烧伤26例28眼,12眼施行角膜缘移植联合部分穿透性角膜移植术,与16眼单纯施行部分穿透性角膜移植术作对照。结果:联合手术组,追踪5～28个月,植片透明率75％,9眼有效地阻止了植片新生血管和假性胬肉的复发,排斥反应发生率33.3％。对照组角膜植片血管新生较多,植片透明率为25％,持续性角膜上皮缺损发生率为50％,排斥反应发生率50％。结论:对严重陈旧性眼部化学伤与热烧伤,施行角膜缘移植联合部分穿透性角膜移植术,有预防术后合并症和改善植片预后的作用。眼科学报1997;13:213—216。
Purpose :To improve the prognosis of grafts for obsolete ocular chemical or thermal bums. Methods :LT+ PK or PK were performed in 28 eyes with severe chemical or thermal burns. The effects of the two groups were compared.
Results: In LT + PK group(12 eyes), during 5 to 28 months of follow-up, the results showed improved visual acuity in 9 eyes (75% ), maintained stable epithelial adhesion without recurrent erosion or persistent epithelial defect in 11 eyes (91.67%),graft transparent in 9 eyes (75% ). Nine eyes (75 %) showed prevented neovascularization and conjunctival tissue from growing into graft. Allograft rejection were identified in 4 eyes (33.33% ). In routine PK group (16 eyes), during 3 to 22 months of follow-up, the results showed improved visual acuity in 4 eyes (25% ), maintained stable epithelial adhesion without recurrent erosion or PCED in 8 eyes (50%), graft transparent in 4 eyes (25%). Four eyes (25%) showed prevented neovascularization and conjunctival tissue from growing into cornea. Conclusions: Combined procedure of LT and PK is an effective treatment for severe ocular chemical or thermal bums. It can reduce persistent corneal epithelial defect and prevent neovascularization and conjunctival epithelial from growing into cornea thus maintaining graft transparent and improving visual acuity. Eye Science 1997; 13; 213 -216.
出处
《眼科学报》
1997年第4期213-216,共4页
Eye Science
关键词
角膜缘移植
角膜移植
化学烧伤
热烧伤
limbal transplantation, keratoplasty, ocular chemical or thermal bums, stem cells
