摘要
体外培养Ｗｉｓｔａｒ系乳鼠肝细胞，分为正常组、实验组和药物对照组，后两组分别加入草苁蓉和人参总皂甙．结果表明，实验组肝细胞脂褐素颗粒随着日龄的增加而明显减少，超氧化物歧化酶活性增强，过氧化脂质产物丙二醛含量降低，尤其是细胞培养的第１４ｄ和第２１ｄ，与正常组相比较均具有显著性差异（Ｐ＜０．０１），与药物对照组相比无显著差异．提示草苁蓉具有与人参相似的药理作用，可以做为抗衰老药物而开发应用．
The suckling mouse hepatocytes were cultured in vitro and treated with Boschniakia rossica(experimental group) and ginsenosides respectively(drug control group). The results indicated that , in the experimental group, the lipofusion granules were significantly decreased with the days of following,and the activity of superoxide dismutase increased and the contents of malondialdehyde reduced , especially on the 14th and 21st day, compared with those of the normal group.
出处
《延边大学医学学报》
CAS
1997年第4期223-226,共4页
Journal of Medical Science Yanbian University
关键词
衰老
草苁蓉
肝细胞
cells,cultured
liver
aging
superoxide dismutase
malondialdehyde
Boschniakia rossica
