摘要
目的了解化疗后骨髓受抑和恢复期血小板平均体积(MPV)变化的情况,以便确定骨髓造血功能开始恢复的早期指标。方法用雅培CELL-DYNR1700血球分析仪对肿瘤病人在化疗过程中MPV的变化进行动态观察,同时测定白细胞数值。结果化疗后骨髓明显受抑,造血功能开始恢复时,MPV为最大值(12.20±2.11fl)。结论MPV可作为化疗后骨髓功能恢复的比较敏感的早期指标,MPV的动态变化,结合白细胞、血小板的观察,有利于指导化疗方案及化疗后造血生长因子的应用。
Objective To investigate the change of mean platelet volumes （MPV） in cancer patients during chemotherapy and its significance in predicating hematopoietic recovery. Methods By using YP - cell - DYNR 1700 autohemocytometer, mean level of platelet volume in 81 patients with tumor was measured during follow - up period after chemotherapy, simuhaneously the white blood cell counts were also detected. Results When bone marrow suppression after chemotherapy began to be recovery, there was the maximum MPV （ 12.20 ± 2.11 ） seen. Conclusion MPV might be used as a sensitive predicative parameter for early bone marrow hematopoietic recovery after chemotherapy, dynamic changes of MPV before and after chemotherapy are helpful for the choice of chemotherapeutic protocols and hemopoietic growth factor.
出处
《临床和实验医学杂志》
2008年第11期20-21,共2页
Journal of Clinical and Experimental Medicine
