摘要
目的:观察鲑鱼降钙素联合维D钙咀嚼片治疗绝经后骨质疏松性腰背痛的临床疗效及治疗前后骨密度变化。方法:应用鲑鱼降钙素及联合维D钙咀嚼片治疗261例绝经后骨质疏松患者腰背疼痛6个月,同期197例患者仅连续口服碳酸钙片及吲哚美辛片6个月做对照,观察两组治疗前后患者腰背部疼痛的改善情况(VAS评分)及腰椎、髋部骨密度变化。结果:鲑鱼降钙素治疗组VAS评分低于对照组(P<0.05),且随治疗时间延长,VAS评分下降更加明显;腰椎及股骨颈骨密度增加高于对照组(P<0.05)。结论:鲑鱼降钙素联合联合维D钙咀嚼片能明显改善绝经后骨质疏松性腰背痛。
Objective： To investigate the clinical effect of calcitonin salmon combined with vitamin Dchewable tablets on postmenopausal osteoporotic lumbodorsal pain, and to compare changes of bone mineral density before and after treatment.Method： 261 patients with postmenopausal osteoporotic lumbodorsal pain underwent a combinative therapy of calcitonin salmon and vitamin D chewable tablets for 6 months; additionally, 197 patients who were orally given calcium carbonate tablets and indometacin for 6 months were regarded as the controls. VAS scores and changes of bone mineral density at lumbar vcrtebra and hip were compared in the two groups before and after treatment.Results：VAS scores in the calcitonin salmon group were significantly lower than those in the control group （P〈0.05）, and the scores were rapidly decreased with the treatment going on.Bone mineral density in the calcitonin salmon group was significantly higher than that in the control group （P〈0.05）.Conclusions： Calcitonin salmon combined with vitamin D chewable tablets could apparently relieve postmenopausal osteoporotic lumbodorsal pain.
出处
《中国医药导刊》
2008年第7期1058-1059,共2页
Chinese Journal of Medicinal Guide
关键词
鲑鱼降钙素
骨质疏松
绝经
calcitonin salmon
osteoporosis
menopause
