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他汀类药物对老年心血管病患者应用研究进展 被引量：3

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摘要 他汀类药物从20世纪80年代应用于临床以来，已被证实可显著降低血清TC浓度，是心血管疾病最有效的治疗药物之一，也是目前心脑血管病防治中最常用的调脂药物。但是，长期以来，他汀类药物获益及药物安全性的循证医学证据，大部分来自非老年患者。在临床证据不足的情况下，加之老年患者各器官功能减退及对他汀类药物代谢的变化，导致老年高危心血管疾病患者，对他汀类药物的使用严重不足，使老年人群不能充分从他汀类药物中获益。因此，他汀类药物在老年人群中是否能同样获益以及长期治疗的安全性成为临床医师关注的问题。
作者 郑刚
机构地区 天津市老年病研究所天津市高血压防治中心天津市第三医院心内科
出处 《中华老年心脑血管病杂志》 CAS 北大核心 2008年第11期867-869,共3页 Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
关键词 心血管疾病 抗胆固醇血症药
分类号 R54 [医药卫生—心血管疾病]
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参考文献15

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同被引文献54

  • 1郑刚,张承宗.解读急性冠状动脉综合征他汀类药物治疗作用的临床证据(二)[J].中国心血管病研究,2004,2(7):491-492. 被引量：12
  • 2郑刚,王佩显.贝特类药物调节代谢综合征血脂异常的作用[J].世界临床药物,2005,26(1):30-33. 被引量：4
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引证文献3

二级引证文献12

中华老年心脑血管病杂志
2008年 第11期

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