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血清CEA、CA199对大肠癌术后复发早期诊断的探讨 被引量:3

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摘要 目的:探讨(癌胚抗原)CEA、(糖链抗原)CA199对大肠癌根治术后患者复发转移的早期诊断价值。方法:采用放射免疫检测法。对57例大肠癌根治术后患者进行定期检测和随访。结果:大肠癌根治术后大多数患者血清CEA、CA199水平在4个月内均下降至正常范围。如果根治术后两者水平仍持续增高未下降至正常,说明手术根治不彻底,可能短期内复发转移。而两者下降至正常后再次出现升高时,则可能出现复发转移情况。有的患者在出现可检测到的复发转移症状、体征或影像学改变前2~5个月,就可发现有血清CEA、CA199水平的持续升高。结论:CEA、CA199对监测大肠癌术后复发转移具有重要作用。以CEA的检出阳性率最高,两者联合检测可以互补不足提高阳性检出率。
作者 尹宣东
出处 《中国社区医师(医学专业)》 2008年第21期170-170,共1页
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