摘要
目的:探讨急性颅脑损伤患者血清CK—BB活性及动态变化的临床意义。方法:逐日监测50例急性脑伤患者血清CK—BB活性,与临床指标对比评价其临床价值,并分析其变化规律与治疗转归、预后的关系。结果:血清CK—BB在伤后早期升高,且与伤情成正相关,CK—BB较快恢复正常是治疗得力、无并发症和预后良好的标志。结论:血清CK—BB是急性脑损伤的可靠、特异性、量化指标,其动态变化规律对判断疗效、迟发病及并发症的早期诊断和预后评估均有重要价值。
Objective: To study the clinical value of serum CK—BB and its dynamic change in patients with acute head injury. Methods: The serum CK—BB activity was measured dynamically day by day by immunoinhibition method in 50 patients with acute head injury. The clinical value was estimated by comparison with the clinical indexes. We also analyzed the relationship between the dynamic changing patterns of head injury. The serum CK—BB、the coming treatment results and the prognosis. Results: The CK—BB activity was in high level of early head injury. And it was in positive coorelation with the severity of head injury. The serum CK—BB activity was recoveried quickly in patients with successful treatment and no complication and favorable prognosis. Conclusions: The serum CK—BB was a reliable, specific, numerical index for the acute head injury. The dynamic changing pattems of serum CK—BB showed substantial value in the evaluation of treatment effects, the early diagnosis of the delayed lesions and complications, as well as the prognostic evaluation.
关键词
颅脑损伤
血清
CK-BB
监测
急性
Head injury Creatine Phosphokinase BB Serum Clinial value
