摘要
目的:探讨藻酸双酯钠致过敏性休克的特点,为临床合理使用藻酸双酯钠提供参考。方法:通过检索《中国医院数字图书馆》1990年1月—2008年3月国内公开发表的医药学期刊中有关藻酸双酯钠致过敏性休克的病例报道26篇中32例进行统计分析。结果:32例中男性13例(40.62%),女性19例(59.38%);年龄40岁以上占90.62%;全部患者均为静脉滴注方式给药;65.62%的患者在用药中发生过敏性休克,并且在各时间段均有出现,34.38%的患者在用药后发生休克,并且主要在用药后30 m in内;过敏性休克的发生与原患疾病和药物剂量无关。结论:掌握藻酸双酯钠所致过敏性休克的特点将有助于临床合理应用。
OBJECTIVE To investigate the characteristics of polysaccharide sulfate （PSS）-induced anaphylactic shock for its rational use in clinic. METHODS Domestic medicine periodicals were searched between January 1990 and March 2008, and thirty - two cases with PSS -induced anaphylactic shock were analyzed. RESULTS Thirty- two patients included 13 men （40.62%） and 19 women （59.38%）. The incidence rate （90.62%） in the age group above 40 was higher than other age groups. PSS were administered by intravenous drip in all cases. 65.62% of the cases developed anaphylactic shock in course of the intravenous drip. 34.38% of the cases developed after the intravenous drip, and most of them happened within 30 minutes. PSS - induced anaphy- lactic shock was independent of patient＇s primary disease and dosage. CONCLUSION Physicians should understand the characteristics of PSS - induced anaphylactic shock in order to benefit the safe and rational use of PSS in clinical practice.
出处
《天津药学》
2008年第5期40-42,共3页
Tianjin Pharmacy
关键词
藻酸双酯钠
过敏性休克
文献分析
polysaccharide sulfate, anaphylactic shock,literature review
