摘要
目的研究胃癌患者确诊时和治疗前后的血红蛋白（Hb）变化和贫血发生情况及其与临床分期、年龄、性别和治疗等方面的关系。方法对我院近1O年的777例住院胃癌患者资料进行回顾分析，研究治疗前后Hb值的变化和贫血的发生例数，并按临床分期和年龄分组进行分析。结果①777例患者确诊时发生贫血例数为464例（59．7％），总贫血发生例数达585例（75．3％）。Ⅰ级43．2％（253／585），Ⅱ级32．1％（188／585），Ⅲ级11．6％（68／585），Ⅳ级13．0％（76／585）。②60岁以上老年组治疗前后的贫血数均高于60岁以下的非老年组，但Hb值均低于非老年组。③治疗后Ⅲ／Ⅳ期患者的贫血发生率明显高于Ⅰ／Ⅱ期患者，并且Hb值也显著低于Ⅰ／Ⅱ期患者。④LogiStiC多因素回归分析证实贫血的发生与年龄、临床分期、化疗和出血有密切的关系，与性别无关。结论胃癌患者有较高的贫血发生率，贫血的发生与年龄、临床分期、化疗和出血有密切的关系。老年患者更易发生贫血。
Objective To study the anemia incidence for 777 patients with stomach cancer ,and analyses correlation between anemia and age, clinical phases , Gender and therapy etc, Methods Analysis both pre-therapy and post-therapy patients＇ hemoglobin（Hb） and study the anemia incidence for 777 patients during ten years（from 1996 to 2005）.Age and clinical phases was used to defining different groups. Results ①The incidence of anemia was 75.3% （585/777） in all and the incidence of anemia was 59.7% （464/777）,when diagnosis were made. The incidence of grade Ⅰ , Ⅱ, Ⅲ and Ⅳanemia were 43.2%（253/585）, 32.1%（188/585）, 11.6%（68/585） and 13.0%（76/585） respectively.②The incidence of anemia in older patients （≥60year） was higher than younger and Hb was lower.③The incidence of anemia in Ⅲ/Ⅳ phases patients was higher than Ⅰ / Ⅱ phases and Hb was lower too.④Four risk factors finally entered into the model of Logistic regression：age, stage chemotherapy and bleeding. Gender was not the risk factors of anemia. Conclusions The incidence of anemia in stomach cancer patients was higher, age, stage, chemotherapy and bleeding were the related factors for anemia in patients with stomach cancer. Anemia trended to be happened easily on older patients.
出处
《国际医药卫生导报》
2008年第21期42-46,共5页
International Medicine and Health Guidance News
关键词
胃癌
贫血
临床分期
年龄
治疗
发生率
Stomach cancer Anemia Clinical staging Age Therapy Incidence
