摘要
目的:探讨奥曲肽治疗肠梗阻的疗效。方法:将150例梗阻随机分为实验组和对照组。对照组给予常规治疗,包括禁食、胃肠减压、纠正水电解质和酸碱平衡紊乱、全胃肠外营养以及应用抗生素;实验组在常规治疗基础上加用奥曲肽(善宁)0.1mg,iH,q8h。观察和比较两组治疗前后临床症状及体征改善情况、胃肠减压量。结果:实验组临床症状明显改善,与对照组相比,腹痛和腹胀的缓解率分别为93.3%、72.0%(P<0.05);肛门恢复排气排便比率分别为88.0%、69.3%(P<0.05);胃肠减压量明显少于对照组,分别为(256±126)mL/d、(578±189)mL/d,(P<0.01)。结论:在常规治疗基础上,应用奥曲肽治疗各种类型肠梗阻,可明显改善临床症状,提高保守治疗的成功率。
Objective： To investigate the effects of Octreotide on intestinal obstruction. Methods： One hundred and fifty patients suffering from intestinal obstruction were randomly divided into control group and experimental group. The patients in the control group were treated with routine therapy including gastrointestinal decompression, intravenous replacement of fluid and electrolytes,total parenteral nutrition and antibiotics.The patients in the experimental group received hypodermic injection Octreotide （q8h）plus routine therapy. Results： The clinical symptoms were significantly improved in the experimental group, the average volume of gastrointestinal decompression reduced in experimental group compared to the control group （256±126）ml/d vs （578±189）ml/d （P〈0.01）. Conclusions： Octreotide combined with routine treatment is an effective method to treat intestinal obstruction.
出处
《岭南急诊医学杂志》
2008年第5期337-338,共2页
Lingnan Journal of Emergency Medicine
关键词
奥曲肽
肠梗阻
疗效
octreotide
intestinal obstruction
efficacy
