摘要
目的:通过对帕金森病患者非运动症状发生率进行排序,探讨非运动症状的临床特征。方法:采用"帕金森病常见的非运动症状30题问卷"对52例帕金森病患者的非运动症状发生率进行排序,并结合性别、族别、临床类型、病程等可能的影响因素对非运动症状中发生率最高、最常见的临床症状进行评估,并进行统计学分析。结果:根据"帕金森病常见的非运动症状30题问卷"调查,具备上述临床表现任何一种症状的总发生率为90.4%(47/52),其中尿急、夜尿症的发生率为69.2%(36/52),为最高、最常见的非运动症状,此后依次为便秘、睡眠障碍、记忆力下降、多汗、焦虑、抑郁、夜间肢体不适感、流涎、不能解释的疼痛等。同时显示,男性尿急、夜尿症发生率(80.7%)较高,与女性相比,两者有统计学差异;病程>5年的28例中有24例出现尿急、夜尿症(85.7%),与病程≤5年的患者相比差异有统计学意义(P<0.05);而汉族与维吾尔族尿急、夜尿症的发生率差异无统计学意义;对于临床症状为僵直型或是震颤型的帕金森病患者其出现尿急、夜尿症的发生率无统计学意义(P>0.05)。结论:帕金森病患者非运动症状发生率非常高,其中尿急、夜尿症的发生率最高、最常见,性别及病程的长短是尿急、夜尿症发生的重要影响因素。因此在诊治过程中应重视帕金森病患者非运动症状,给予积极治疗,以改善帕金森病患者的生活质量。
Objective：To arrange the non-motor symptoms of Parkinson＇s disease in order of their incidence and to explore their clinical features.Methods：＂Questionnaire of non-motor symptoms in patients with Parkinson＇s disease＂ was used in 52 cases of patients with Parkinson＇s disease,symptoms incidence of non-campaign assessment and integration of gender,nationality,clinical type,duration and other factors on the possible impact were arranged in order.The highest,the most common symptoms of non-campaign were evaluated and statistically analysed.Results：According to ＂questionnaire of non-motor symptoms in patients with Parkinson＇s disease＂ that survey,with the performance of any of the clinical symptoms of the total rate was 90.4%（47/52）,the rate of urgency of urine,nocturia was 69.2%（36/52）,that consisted the highest,the most common non-motor symptoms,then followed by constipation,sleep disorders,memory loss,sweating,anxiety,depression,unpleasant sensations in limbs at night or while resting discomfort at night,drooling,and unknown pain.At the same time,the incidence of urgency and nocturia in men was（80.7%）higher than that in women,with a significant difference;course〉5 years of 24 cases in 28 cases of urgency and nocturia（85.7%）,and compared to the patients with course≤5 years had a significant difference（P〈0.05）;urgency and nocturia in than and Uygur there was no significant difference;for the clinical symptoms of tremors or rigidity of patients with Parkinson＇s disease in its urgency and nocturia was not significant（P〉0.05）.Conclusion：Non-motor symptoms of Parkinson＇s disease have a very high rate,urgency and nocturia have the highest rates,the most common,sex,and the length of the course are the important factors of urgency,nocturnal enuresis.Therefore,in the process of diagnosis and treatment of patients with Parkinson＇s disease should attach importance to non-motor symptoms,and active treatment should be done to improve the quality of life.
出处
《新疆医科大学学报》
CAS
2008年第9期1173-1175,共3页
Journal of Xinjiang Medical University
关键词
帕金森病
非运动症状
尿急
夜尿症
Parkinson＇s disease
non-motor symptoms
urgency
nocturia
