摘要
目的:观察芪苈强心胶囊联合西药治疗中、重度慢性充血性心力衰竭(CHF)的疗效及安全性。方法:将80例CHF患者随机分为两组,对照组给予ACEI类、利尿剂、小剂量地戈辛片和酒石酸美托洛尔片,治疗组在对照组治疗基础上加服芪苈强心胶囊(4粒/次,每日3次)、曲美他嗪片(20mg/次,每日3次),4周时比较两组治疗效果。结果:治疗组心功能改善率、总有效率、左室射血分数(LEVF)提高率分别为:97.5%、100%、(30±5)%,而对照组分别为87.5%、92.5%、(13±4)%,两组比较差异有统计学意义(P<0.05或P<0.01),治疗组生活质量改善优于对照组(P<0.01),两组均未发现明显不良反应。结论:芪苈强心胶囊合用曲美他嗪及其他西药治疗CHF具有明显疗效和良好的安全性。
Objective：To observe the therapeutic effect of Qiliqiangxin capsule combined with western medicine on moderate and severe chronic contrative heart faicure（CHF）.Methods：40 patients with CHF in control group were treated with ACEI uretica small dose of beta-blocker tablet and digoxin .the 40 patients in treatment group on the basis of control group,were treated by Qiliqiangxin capsule four pills once three times a day and trimetazidine 20rag once three times a day, the therapeatic effects were observed and compared after four-weeks treatment in the two groups.Results：The total effective rate of cardiac function improvement,total effective rate of improvement of TCM symptoms and increasing rate of left ventricle ejection fraction （LVEF）in treatment group were 97.5%,100%,（30± 5）% respectively,but which in control group were 87.5%,92.5%,（15± 4）%,there was a significant difference between the two groups （P 〈0.05 or P 〈0.01）,the side effects were not found in both groups.Conclusion：In the treatment of moderate and severe chronic contractive heart failure,Qiliqiangxin capsule combined with western medicine could improve cardiac function effectively,alleviate clinical symptoms and increase LVEF with safety.
出处
《实用中西医结合临床》
2008年第5期5-6,共2页
Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine
