摘要
目的探讨青少年空腹血糖受损（IFG）的相关危险因素。方法秦皇岛地区一项3937名13-18岁青少年的横断面调查。根据空腹血糖分为空腹血糖正常组和空腹血糖受损组（IFG组）。测量身高、体重、腰围、血压、TG、TC、HDL-C、LDL-C水平。结果共检出IFG136例（3.5%）,男女IFG检出率分别为3.9%和3.1%,两性间比较无统计学差异（P=0.177）。IFG组具有2项以上心血管危险因素的危险性是空腹血糖正常组青少年的1.889倍（95%CI1.125-3.171）。IFG组45.6%存在糖尿病家族史。多元逐步回归显示年龄、腰围、胆固醇均为独立影响因素。结论青少年群体中IFG相当多见,并已开始导致心血管危险因素聚集。遗传因素、腹型肥胖及脂代谢异常是IFG的危险因素。
Objective To examine the risk factors for impaired fasting glucose （IFG） and its relationship with cardiovascular risk /actors in adolescents. Methods A cross-sectional study was conducted on 3937 adolescents aged 13-18 years. IFG was defined as a fasting glucose of 5. 6 to 7. 0mmol/L. Height,weight, waist circumference（WC）, blood pressure, fasting plasma glucose（FPG）, total cholesterol（TC）, triglyceride（TG） and high-density iipoprotein cholesterol （HDL-C） were measured. Results （1）The prevalence of IFG in total population was 3.5% and similar between boys and girls （3.9% vs 3. 1%, P=0. 177）. （2） Odds ratio for two and over cardiovascular risk factors in IFG group was 1. 889 times （95%CI 1. 125-3. 171）versus normal fasting glucose group. （3）The prevalence of family history of diabetes was higher in IFG group（45.6 T ）. Multiple linear regression analysis using FPG as a dependent variable showed that age, WC and TC were significantly independent predictors. Conclusions The prevalence of IFG in adolescents is high. Adolescents with IFG show the clustering of cardiovascular risk factors. Genetical susceptibility, abdominal obesity and dyslipidemia are the main risk factors for adolescents IFG.
出处
《中国糖尿病杂志》
CAS
CSCD
北大核心
2008年第10期592-594,共3页
Chinese Journal of Diabetes
基金
河北省科技厅科技支撑项目(072761528)
关键词
空腹血糖受损
青少年
心血管危险因素
Impaired fasting glucose
Adolescent
Cardiovascular risk factors
