摘要
目的探讨原发性闭角型青光眼与糖代谢之间的关系。方法检测３６例原发性闭角型青光眼患者和４０例正常人的口服葡萄糖耐量试验（葡萄糖７５ｇ）及血清胰高血糖素、Ｃ—肽和皮质醇水平。结果病人组糖耐量异常率及空腹血糖和血清皮质醇水平比正常对照组明显增高（Ｐ＜０．０５～Ｐ＜０．０１），而血清胰高血糖素及Ｃ—肽水平却未相应增高。结论原发性闭角型青光眼患者的胰岛功能减退，应注意改善该病患者的胰岛功能和纠正糖耐量异常。
ObjectiveTo investigate the relation between primary angleclosure glaucoma and glucose metabolism.MethodsThe oral glucose tolerance test(OGTT,glucose 75 g)and the serum levels of glucagon,Cpeptide and cortisol were measured in 36 patients with primary angleclosure glaucoma and 40 agematched normal controls.ResultsThe percentage of impaired glucose tolerance and the serum level of cortisol were significantly higher in glaucoma than in the normal controls(P<0.05～P<0.01).The serum levels of glucagon and Cpeptide were not significantly different between the two groups.ConclusionIt is indicated that the pancreatic islet function is insufficient in glaucoma.It could be important for the patients with primary angleclosure glaucoma to improve the pancreatic islet function and glucose tolerance.
出处
《眼科研究》
CSCD
1997年第4期262-263,共2页
Chinese Ophthalmic Research
关键词
闭角型青光眼
胰岛功能
葡萄糖耐量
青光眼
ngleclosure glaucoma pancreatic islet function glucose tolerance
