摘要
目的探讨急性视网膜坏死（acute retinalnecrosis，ARN）综合治疗时机选择及疗效。方法ARN患者15例（18只眼），病程1周至6月，初诊视力：光感、手动和数指各2只眼，0．02～0．1者4只眼，0．12-0．4者6只眼，0．5、0．6各1只眼。所有患者确诊后均全身使用抗病毒药物阿昔洛韦或更昔洛韦，并根据病情不同采用玻璃体腔注药、激光光凝及玻璃体切割术等治疗方法，随访3—26月，平均（14．3±6．5）月。结果14只眼在单纯全身抗病毒治疗后5只眼视力提高，8只眼经玻璃体腔注药后视力提高4只眼，行玻璃体切割术9只眼，术后均视网膜在位，7只眼视力提高，2只眼无提高。结论ARN患者早期诊断是治疗的关键，早期全身抗病毒治疗是基础，玻璃体腔注药联合预防性眼内激光光凝及适时的玻璃体切割术是治疗ARN的有效手段。
Objective To discuss the clinical effects and the selection of methods and juncture for the treatment of acute retinal necrosis （ARN）.Methods Fifteen cases （18eyes）ofARN.Course of disease was 1 week to 6 months.Preoperative visual acuity were light perception （LP）,hand movement （HM）and counting fingers（ CF ）, each in 2 eyes, 0.02-0. 1 in 4 eyes, 0.12-0.4 in 6 eyes, 0.5 and 0.6 in each 1 eye.All of the patients treated with antivirus drug by intervenous drop infusion,then they were treated with Ganciclovir which was injected into vitreous cavity, Endophotocoagulation or vitrectomy based on those conditions.Followed up from 3 to 26 months.Results After the treatment of antivirus drug intervenous drop infusion, 5 of the 14 eyes had elevated visual acuity.4 eyes visual acuity increased after treated with Ganciclovir which was injected into vitreous cavity in 8 eyes.All of 9 eyes obtained anatomic success after vitrectomy,and 7 eyes of 9 eyes after surgery had up visual acuity.Conclusions Early diagnosis is the key of the treatment of ARN, antivirus drug by intervenous drop infusion in earlier period is basal therapy,vitreous cavity injection combined Endophotocoagulation and vitrectomy are effective methods for the acute retinal necrosis.
出处
《中国实用眼科杂志》
CSCD
北大核心
2008年第10期1097-1100,共4页
Chinese Journal of Practical Ophthalmology
关键词
急性视网膜坏死
注射
玻璃体切割
眼内光凝
Acute retinal necrosis
Injection
Vitrectomy
Endophotocoagulation
