摘要
意外胆囊癌的诊断率随着检查技术的提高及腔镜手术的应用率上升而提高,目前仍未出现一套统一的、规范化的治疗程序,本文总结、探讨意外胆囊癌的处理原则及预后因素,以期为意外胆囊癌的临床处理提供一定的方向。查阅大量文献,比较意外胆囊癌不同分期、不同术式的治疗效果,并分析相关影响因素及预后因素。通过对比研究发现,在众多影响因素中,肿瘤侵犯深度、淋巴结侵犯、术中胆漏、切除范围及二次根治手术为意外胆囊癌重要预后因素,其中肿瘤的侵犯深度是最为重要的预后因素。鉴于以上对预后有重要影响的因素,术前应重视高危因素、严格把握LC手术指征、术中必须剖视胆囊标本、遇相应情况及时中转开腹手术或进行二次根治手术对改善意外胆囊癌患者的预后有积极意义。
Unsuspected gallbladder carcinoma （UGC） is defined as carcinoma of the gallbladder firstly diagnosed at the histological examination of the resected gallbladder. More and more cholecystectomies have been laparoscopically performed all over the world. The incidence of UGC becomes much higher. In this article we discussed the prognostic factors and the management of UGC, in an effort of providing suggestions to the treatment of UGC. Based on literatures, we compared the effect of different surgical procedures on UGC of different T stage and analyzed the prognostic factors. Tumor infiltrative depth, lymph node state, intraoperative bile leakage, excision extent, and second radical excision were the prognostic factors of UGC, among which tumor infiltrative depth is the most important factor. For control of UGC and improvement of its prognosis, we should pay close attention to the risk factors of UGC, standardize the implication of LC, check the dissected gallbladder during surgery, and turn to OC in time or make second radical excision early after LC.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2008年第19期1135-1138,共4页
Chinese Journal of Clinical Oncology
关键词
意外胆囊癌
腹腔镜胆囊切除术(LC)
二次手术
Unsuspected gallbladder carcinoma （UGC）
Laparoscopic cholecystectomy （LC）
Secondary surgery
