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慢性肾脏病患者血清PTH与BMP-2的变化及意义

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摘要 选择慢性肾脏病(CKD)患者65例和健康查体者20例(对照组),根据肾小球滤过率(GFR)将CKD患者分为五组,分别采用化学发光法和酶联免疫吸附法测定血清血清甲状旁腺激素(PTH)及骨形态发生蛋白-2(BMP-2)浓度,分析血清PTH及BMP-2浓度变化的规律。结果CKD患者血清PTH、BMP-2浓度均明显高于对照组(P<0.01);CKD患者血清BMP-2浓度与PTH呈正相关(r=0.678,P=0.006)。认为CKD患者血清PTH及BMP-2浓度随肾功能损害程度加重逐渐升高,提示PTH、BMP-2与CKD患者病情进展有一定关系。
作者 范旗 赵燕凌 甘西伦
机构地区 泸州医学院附属医院
出处 《山东医药》 CAS 北大核心 2008年第28期74-75,共2页 Shandong Medical Journal
关键词 肾功能衰竭 甲状旁腺激素类 骨形态发生蛋白-2
分类号 R692 [医药卫生—泌尿科学]
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参考文献3

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二级参考文献20

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山东医药
2008年 第28期

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