期刊文献+

老年不稳定型心绞痛患者外周血管内皮功能的变化及意义 被引量:3

暂未订购
导出
摘要 选择60例老年不稳定型心绞痛(UAP)患者(UAP组)和30例正常老年人(对照组),分别应用彩色多普勒超声测定外周血管肱动脉内皮依赖性舒张反应,比较两组肱动脉气囊加压前后的血管内径、血流速度变化和血浆一氧化氮(NO)浓度。结果UAP组肱动脉加压前后的血管内径和血流速度变化明显小于对照组(P<0.05),NO浓度明显低于对照组(P<0.01);UAP组肱动脉加压前后的血管内径变化与血浆NO浓度呈明显正相关(r=0.83,P<0.01)。认为老年UAP患者的血管内皮功能下降,尽早采取措施改善血管内皮功能有助于逆转血管内皮功能失调,减少冠心病事件的发生率。
出处 《山东医药》 CAS 北大核心 2008年第28期34-35,共2页 Shandong Medical Journal
  • 相关文献

参考文献5

  • 1马礼坤,顾统元.内皮功能异常与冠状动脉疾病[J].心血管病学进展,2000,21(5):262-265. 被引量:30
  • 2Celermajer DS, Sorensen KE, Cooch VM, et al. Non-mvasive detection of endothelial dysfunction in children and adults at risk of atherosclerosis [ J ]. Lancet, 1992, 340 ( 5 ) : 111-414.
  • 3Ridker PM, Cusham M, Stampfer JM, et al. Plasma concentration of C-reactive protein and risk of develeoping peripheral vascular disase[J]. JAM Coll Cardiol, 2003, 31(11) : 731-737.
  • 4Mehta JL, Saldeen TG, Rand K. Interaction role of infection, inflammation and traditional risk factors in atherosclerosis and coronary disease[J]. JAM Coll Cardiol, 2003, 98: 1127-1134.
  • 5Pratri P, Vanuzzo D, Cassaroli M, et al. Prevalence and dominanls of carotid atherosclerosis in a general population[ J ]. Stroke, 2005, 23(12) : 1705-1711.

二级参考文献24

  • 1[1]Ludmer PL,Selwyu AP,Sbook TL,et al. Paradoxical vssoconstriction induced by acetylcholine in atherosclerotic coronary arteries[J]. N Engl J Med,1986,325:1046
  • 2[2]Osborne JA,Lento PH,Siegfride MR,et al. Cardiovasculer effects of acute hypercholesterolemia in rabbits: Reversal with lovastatin treatment [J]. J Clin Invest, 1989,83: 465
  • 3[3]Andreas MZ, Helmut D, Bernwards, et al. Endothelium-mediated cotonary bloodflow modulation in humans. Effect of age,atheroscleroais ,hypercholssterolemia,and hypertensin[J]. J Clin Invest,1993,92:652
  • 4[4]Keld ES,David SC,Dimilri G,et al. Impairment of endothelium dependent dilation is an early event in children with familial hypercholssterolemia and is related to the lipoprotein(a) level[J] J Clin Invest, 1994,93:50
  • 5[5]Karan GR,Ravin N,Helen MS,et al. Evidence that selective endothelial dysfunction may occur in the absence of augiographic or ulttasound atherosclerosis in patients with risk factors for atherosclerosis [J]. J Am Coll Cardiol, 1994,23:833
  • 6[6]Egashira K, Inou T,Hirooka Y,et al. Evidence of impaired endothelium-dependent coronary vasoditation in patients with angina pectoris and normal coronary angiograms[J]. N Engl J Med,1993,328:1659
  • 7[7]Helmut D. Endothelial dysfunction:clinical implications[J]. Prog Cardiovasc Dis, 1997,34:287
  • 8[8]Wennmalrn A. Endothelial nitric oxide and cardisvascular disesse[J]. J Intern Med, 1994,235: 317
  • 9[9]Quyyumi AA,Dakak N,Andrews NP,et al. Contribution of nitric oxide to metabolic coronary vasodilation in human heart[J]. Circulation, 1995,92:320
  • 10[10]Scott K and Peter G. Role of endothelial dysfunction in coronary artery dis ease ani implications for therapy[J]. Am J Cardiol,1997,80(9A):112

共引文献29

同被引文献15

二级引证文献27

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部