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“乳炎康注射液”消除奶牛乳房炎致病菌对β-内酰胺类耐药性的研究 被引量:3

Study on Effect of Eliminating the Main Pathogenic Bacteria of Cow Mastitis by Ruyankang Injection on Drug Resistance of β-lactam Antibiotics
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摘要 [目的]研究“乳炎康注射液”对奶牛乳房炎主要致病菌耐药性的消除作用。[方法]观察奶牛乳房炎主要致病菌对氨苄青霉素等5种β-内酰胺类抗生素的耐药性,并通过筛选耐药菌,研究“乳炎康注射液”对其耐药性的消除作用。[结果]奶牛乳房炎主要致病菌对先锋霉素V高敏,对羧苄青霉素比较敏感,对氨苄青霉素、阿莫西林、青霉素G的敏感性低,并且产生了不同程度的耐药性。经“乳炎康注射液”感触后,奶牛乳房炎主要致病菌对β-内酰胺类抗生素的耐药率明显下降,且原来敏感药物的抑菌圈扩大了1.2~2.3mm。[结论]“乳炎康注射液”对奶牛乳房炎主要致病菌对β-内酰胺类抗生素的耐药性有一定的消除作用。 [ Objective ] The aim was to study the eliminating effect of the Ruyankang injection on drug resistance of the main pathogenic bacteria of cow mastitis. [ Method ] The drug resistances of the main pathogenic bacteria of cow mastitis to 5 kinds of β-lactam antibiotics such as ampicillin were observed and the eliminating effect of the Ruyankang injection on the drug resistance was studied after the drug-resistant bacteria were screened. [ Result] The main pathogenic bacteria of cow mastitis had high sensitivity to cephalosporin V and relative sensitivity to carbenicillin. They had low sensitivity to ampicillin, amoxicillin, penicillin G and produced drug resistance on them to a different degree. The resistance rate of the main pathogenic bacteria of cow mastitis on the β-lactam antibiotics was decreased obviously after the pathogenic bacteria were affected by Ruyankang injection and the inhibition zone of the sensitive drugs was enlarged 1.2 -2.3 mm. [ Conclusion] Ruyankang injection had certain eliminating effect on the drug resistances of the main pathogenic bacteria of cow mastitis to the β-laetam antibiotics.
作者 叶刚 李英伦
出处 《安徽农业科学》 CAS 北大核心 2008年第26期11340-11343,共4页 Journal of Anhui Agricultural Sciences
关键词 “乳炎康注射液” 奶牛乳房炎 致病菌 Β-内酰胺类抗生素 耐药性 Ruyankang injection Cow mastitis Pathogenic bacteria β-laetam antibiotic Drug resistance
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