摘要
为探讨胆碱能神经功能和胃窦部幽门螺杆菌（Ｈｐ）感染与慢性胃炎（ＣＧ）、消化性溃疡（Ｐｕ）的关系，测定７６例慢性胃炎和消化性溃疡患者全血和胃液乙酰胆碱（Ａｃｈ），并检测胃窦部幽门螺杆菌的感染指标，同时测定１８例健康对照组全血Ａｃｈ。结果：Ａｃｈ在ＣＧ、Ｐｕ和对照组间、不同胃炎程度间、活动性与非活动性胃炎间以及Ｈｐ阳性与阴性间均无显著性差异；Ｈｐ感染率在Ｐｕ患者高于ＣＧ、活动性高于非活动性胃炎，并随胃炎程度加重而增高；清除Ｈｐ后Ｐｕ愈合、胃炎改善。提示Ｈｐ感染是ＣＧ和Ｐｕ的病因之一，胆碱能神经功能紊乱可能不是其主要病因。
Whole blood and gastric juice acetylcholine (Ach) levels of 76 chronic gastritis (CG) and peptic ulcer (Pu) patients,and whole blood acetylcholine levels of 18 healthy controls were measured At the same time,helicobacter pylori (Hp) from the patients' gastric antrum were also examined The results showed that there were no significant differences in the Ach levels:among CG,Pu patients and the chontrols;in the different degrees of gastric inflammation;between active gastritis and non active gastritis patients;and between Hp positive and negative patients The Hp positive rate was higher in Pu patients than in CG patients,and higher in the active gastritis patieits than in the non active gastritis patients And such Hp positive rate increased along with the severity of the gastric inflammation.Pu healed and the gastric inflammation improved with the eradication of Hp The results suggest that Hp infection is one of the agents involved in the pathogenesis of CG and Pu,and that the disturbance of the colinergic nerve function may not be the main causal factor responsible for the pathogenesis of these two diseases
出处
《广西医科大学学报》
CAS
1997年第2期6-9,共4页
Journal of Guangxi Medical University
关键词
乙酰胆碱
幽门螺杆菌
胃炎
消化性溃疡
acetylcholine
antrum helicobacter pylori
gastritis
peptic ulcer
