摘要
单核苷酸多态性(Single nucleotide polymorphisms,SNPs)是许多生物体最丰富的遗传变异形式。林木是重要的植物类群和陆地植物生态系统的重要组成部分,SNP作为新的分子标记已应用于松、杨、黄杉、桉和云杉等属的多个树种的遗传育种学研究,获得了包括核苷酸多样性、连锁不平衡及群体结构等相关的遗传信息,这些研究主要建立在对候选基因序列进行测序分析的基础上。基于SNP的关联遗传学分析或连锁不平衡(Linkage disequilibrium,LD)作图,已成为研究林木复杂数量性状的理想工具,对桉树和火炬松的关联遗传学研究发现,多个基因内的SNP位点与不同的木材性状相关联。利用SNP标记对林木遗传参数的估算从不同程度上揭示了林木群体进化规律及其生态学意义。SNP标记在林木中应用的不断深入,必将极大地推动林木遗传育种学研究的发展。
Single nucleotide polymorphisms （SNPs） are the most abundant form of genetic variation in many organisms. Forest is an important plant group and key component of the terrestrial plant ecosystem. As a new marker system, SNP has been applied in genetic and breeding studies in some tree species of genera Pinus, Populus, Pseudotsuga, Eucalyptus, and Picea, and the related genetic information, such as nucleotide diversity, linkage disequilibrium （LD） and population structure has been generated. These studies are mainly based on sequencing and analysis of candidate genes. SNP-based association genetics analysis or LD mapping has become a useful tool for dissection of complex traits in forest trees. Association studies in Eucalyptus spp. and Pinus taeda L. found that some SNP sites in various genes were associated with distinct wood property traits. Meanwhile, estimation of genetic parameters has revealed the evolutionary and ecological significance at different extents in several tree species. Intensive applications of SNP approach are expeted to greatly accelerate the development of research on forest genetics and breeding.
出处
《遗传》
CAS
CSCD
北大核心
2008年第10期1272-1278,共7页
Hereditas（Beijing)
基金
国家"十一五"科技支撑计划项目(编号:2006BAD01A15)
国家高技术研究发展计划项目(863项目)(编号:2006AA100109)资助~~
关键词
林木
单核苷酸多态性
核苷酸多样性
连锁不平衡
关联遗传学
forest trees
single nucleotide polymorphisms （SNPs）
nucleotide diversity
linkage disequilibrium （LD）
association genetics
