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黄酮类化合物对前列腺癌细胞的凋亡诱导作用 被引量：3

Flavone Compound Induces the Apoptosis of Prostate Cancer Cells
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摘要 黄酮类化合物是广泛存在于植物中的一类多酚类化合物,具有广泛的生物活性,近年来研究发现其在抗肿瘤方面具有显著疗效,主要表现在抗细胞增殖、诱导细胞凋亡、干预细胞信号转导和增强抑癌基因活性及抑制癌基因表达等方面。本文就黄酮类化合物诱导前列腺癌细胞凋亡的作用机制进行综述。 Flavone compound is a polyphenolic compound widely existing in plants and has an extensive biological activity. In recent years , it has been found to have a significant anti-cancer effect, as in combating cell proliferation, inducing cell apoptosis, interfering with cellular signal transduction, increasing the activity of the cancer repressor gene and inhibiting the expression of oncogene. This paper reviews the mechanism by which flavone compound, induces the apoptosis of prostate cancer cells.
作者 张丽 商学军 黄宇烽
机构地区 南京理工大学化工学院 南京军区南京总医院解放军临床检验医学研究所
出处 《中华男科学杂志》 CAS CSCD 2008年第9期842-845,共4页 National Journal of Andrology
关键词 黄酮类化合物 前列腺癌 凋亡 flavone compound prostate cancer apoptosis
分类号 R737.25 [医药卫生—肿瘤]
  • 相关文献

参考文献19

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  • 2Haddad AQ, Venkateswaran V, Viswanathan L, et al. Novel antiproliferative flavonoids induce cell cycle arrest in human prostate cancer cell lines [ J ]. Prostate Cancer Prostatic Dis, 2006, 9 (1) :68-76.
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二级参考文献39

  • 1张世革,王益华,丁毅,吴烨.晚期前列腺癌联合雄激素阻断治疗的长期随访[J].中华男科学杂志,2005,11(10):770-771. 被引量：2
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  • 9Sun X M, MacFarlane M, ZhuangJ, etal. Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis. J Biol Chem, 1999, 274(8):5 053.
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共引文献54

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引证文献3

二级引证文献19

中华男科学杂志
2008年 第9期

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