期刊文献+

慢性心力衰竭住院患者药物治疗与指南的差距 被引量:8

Margin between Pharmacotherapy Taken by the Inpatients with Chronic Heart Failure and Guideline
原文传递
导出
摘要 目的:评价慢性心力衰竭(CHF)住院患者的治疗用药。方法:采用回顾性分析方法,将384例CHF住院患者分为左心室射血分数(LVEF)正常组和LVEF减少组,调查其使用利尿药、螺内酯、血管紧张素转换酶抑制剂/血管紧张素Ⅱ受体拮抗药、β-受体阻滞药、洋地黄制剂、非洋地黄类正性肌力药和钙离子通道阻滞药的情况。结果:LVEF正常组在β-受体阻滞药、螺内酯、洋地黄制剂治疗方面与2005年美国心脏病学会/美国心脏协会的《慢性心力衰竭治疗指南》存在差距。结论:LVEF正常的CHF合理用药水平有待提高。 OBJECTIVE: To evaluate therapeutic medication in the inpatients with chronic heart failure (CHF). METHODS: In this retrospective study, 384 inpatients with chronic heart failure were enrolled and divided into normal left ventricular ejection fraction (LVEF) group and reduced LVEF group. The use of diuretics, spironolactone, angiotensin converting enzyme inhibitors/angiotensin Ⅱ receptor blockers, beta-adrenergic receptor blockers, digitalis preparations, non- digitalis positive inotropic drugs and calcium antagonists in these patients were analyzed respectively. RESULTS: There was disparity between ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult and use of beta- adrenergic receptor blockers, spironolactone and digitalis preparations taken by CHF inpatients with normal LVEF. CONCLUSION: The level of rationa use of drugs taken by the CHF inpatients with normal LVEF remains to be improved.
出处 《中国药房》 CAS CSCD 北大核心 2008年第29期2309-2311,共3页 China Pharmacy
基金 广东省医院药学研究基金项目(200703)
关键词 慢性心力衰竭 左室射血分数 药物治疗 药学服务 Chronic heart failure Left ventricular ejection fraction Pharmacotherapy Pharmaceutical care
  • 相关文献

参考文献5

  • 1慢性收缩性心力衰竭治疗建议[J].中华心血管病杂志,2002,30(1):7-23. 被引量:2409
  • 2叶任高,陆再英.内科学[M].第6版.北京:人民卫生出版社,2007:466-472.
  • 3Pitt B, Zannad F, Remme WJ, et al, For the randomized aldactone evaluation study investigators, the effect of spironolactone on morbidity and mortality in patients with severe heart failure [J ]. N Engl J Med, 1999,341 (10) : 709.
  • 4The Digitalis Investigation Group. The effect of digoxin on mortality and morbidity in patients with hear failure [J ]. N Eng J Med , 1997, 336(8) : 525.
  • 5吴宁.钙拮抗剂在慢性心力衰竭治疗中的地位[J].中华心血管病杂志,2002,30(7):445-446. 被引量:14

二级参考文献7

  • 1Elkayam U,Weber L,McKay C,et al.Differences in hemodynamic response to vasodilation due to calcium channel antagonism with nifedipine and direct-acting agonism with hydraltzine in chronic refractory congestive heart failure[].The American Journal of Cardiology.1984
  • 2Elkayam U,Amin J,Mehra A,et al.A prospective, randomized,double-blind, crossover study to compare the efficacy and safety of chronic nifedipine therapy with that of isosorbide dinitrate and their combination in the treatment of chronic congestive heart failure[].Circulation.1990
  • 3Elkayam U,Weber L,McKay C,et al.Spectrum of acute hemodynamic effects of nifedipine in severe congestive heart failure[].The American Journal of Cardiology.1985
  • 4Cheophas TJ,van Marum R.Mata-alalysis of efficacy and safety of second-generation dihydropyridine calcium channel blockers in heart failure[].The American Journal of Cardiology.2001
  • 5Elkayam U,Gleicher N.Comparison of hemodynamic responses to nifedipine and nitroprusside in severe chronic congestive heart failure[].The American Journal of Cardiology.1984
  • 6Chew CY,Hecht HS,Collett JT,et al.Influence of severity of ventricular dysfunction on hemodynamic responses to intravenously administered verapamil in ischemic heartdisease[].The American Journal of Cardiology.1981
  • 7Consensus recommendations for the management of chronic heart failure.On behalf of the membership of the advisory council to improve outcomes nationwide in heart failure[].The American Journal of Cardiology.1999

共引文献2496

同被引文献59

引证文献8

二级引证文献97

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部