摘要
目的:评价慢性心力衰竭(CHF)住院患者的治疗用药。方法:采用回顾性分析方法,将384例CHF住院患者分为左心室射血分数(LVEF)正常组和LVEF减少组,调查其使用利尿药、螺内酯、血管紧张素转换酶抑制剂/血管紧张素Ⅱ受体拮抗药、β-受体阻滞药、洋地黄制剂、非洋地黄类正性肌力药和钙离子通道阻滞药的情况。结果:LVEF正常组在β-受体阻滞药、螺内酯、洋地黄制剂治疗方面与2005年美国心脏病学会/美国心脏协会的《慢性心力衰竭治疗指南》存在差距。结论:LVEF正常的CHF合理用药水平有待提高。
OBJECTIVE: To evaluate therapeutic medication in the inpatients with chronic heart failure (CHF). METHODS: In this retrospective study, 384 inpatients with chronic heart failure were enrolled and divided into normal left ventricular ejection fraction (LVEF) group and reduced LVEF group. The use of diuretics, spironolactone, angiotensin converting enzyme inhibitors/angiotensin Ⅱ receptor blockers, beta-adrenergic receptor blockers, digitalis preparations, non- digitalis positive inotropic drugs and calcium antagonists in these patients were analyzed respectively. RESULTS: There was disparity between ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult and use of beta- adrenergic receptor blockers, spironolactone and digitalis preparations taken by CHF inpatients with normal LVEF. CONCLUSION: The level of rationa use of drugs taken by the CHF inpatients with normal LVEF remains to be improved.
出处
《中国药房》
CAS
CSCD
北大核心
2008年第29期2309-2311,共3页
China Pharmacy
基金
广东省医院药学研究基金项目(200703)
关键词
慢性心力衰竭
左室射血分数
药物治疗
药学服务
Chronic heart failure
Left ventricular ejection fraction
Pharmacotherapy
Pharmaceutical care