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索拉非尼治疗晚期恶性肿瘤不良反应的观察及护理 被引量:6

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摘要 目的探讨索拉非尼不良反应的临床观察要点与护理措施。方法对10例使用索拉非尼口服化疗的晚期恶性肿瘤患者的不良反应进行观察与护理,尤其是手足综合征、皮肤反应的预防与护理及高血压的护理和消化系统症状的观察与护理。结果治疗期间,仅1例前列腺癌患者在服药8个月后因多器官功能衰竭死亡;主要不良反应发生情况:手足综合征8例,消化道症状7例,疲劳7例,血压升高6例,皮肤反应3例。结论索拉非尼除具有与其他化疗药物相似的不良反应如骨髓抑制、全身反应等,还包括手足综合征、皮肤反应、血压升高及腹泻等;治疗过程中,应密切观察患者的不良反应,并及时采取相应的护理措施,使患者顺利完成治疗。
出处 《解放军护理杂志》 2008年第19期69-70,共2页 Nursing Journal of Chinese People's Liberation Army
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