摘要
目的探讨免疫球蛋白及补体在慢性肾功能衰竭和急性肾功能衰竭鉴别诊断中的临床意义。方法对80例慢性肾功能衰竭患者、64例急性肾功能衰竭患者和50例健康对照者采用速率散射比浊法检测免疫球蛋白及补体。结果(1)慢性肾功能衰竭患者与健康对照相比较,IgG、IgM和补体C3、C4有显著性差异(分别是P<0.001、P<0.001、P<0.001和P<0.05);(2)急性肾功能衰竭与健康对照相比较,IgG、IgA有显著性差异分别是(P<0.05和P<0.001);(3)急性肾功能衰竭与慢性肾功能衰竭患者相比较,IgG、IgM和补体C3、C4有显著性差异(分别是P<0.01、P<0.001、P<0.001和P<0.05)。结论血清免疫球蛋白及补体的检测对慢性肾功能衰竭和急性肾功能衰竭的鉴别诊断有重要临床意义。
Objective To investigate the clinical significance of determination of immunoglobulin（Ig）and complement between chronic renal failure（CRF） and acute renal failure（ARF）Methods Ig and complement in 144 patients and 50 healthy controls were determined by rate nephlemetry respectively.Results The levels of IgG,IgM,complement3（C3） and complement4（C4）in CRF were significantly lower than that in healthy controls （P〈0.001,P〈0.001,P〈0.001 and P〈0.05）.IgG in ARF was lower than that in healthy controls（P〈0.05）,but IgA was significantly higher（P〈0.001）. IgG,IgM,C3 and C4 in CRF were significantly lower than that in ARF.Coaclusion The determinaton Ig and complement in serum between CRF and ARF have an important clinical significance.
出处
《江西医药》
CAS
2008年第9期894-896,共3页
Jiangxi Medical Journal
