摘要
作者通过NIH种小鼠模型和平板免疫溶血试验(PIH)及SPA协同凝集试验检测了11株空肠弯曲菌产生侵袭和肠毒素的能力。经光镜及电镜观察,10株菌能侵入小鼠肠壁组织内。7株菌SPA协同凝集试验阳性,即能产不耐热肠毒素(CJT)的占63.6％,而PIH阳性的4株,占36.4％。表明:①成都地区的空肠弯曲菌既有侵袭力又能产生肠毒素,具有多重致病力。②患儿临床表现与菌株致病机理无确切关系。
The invasiveness and heat-labile enter-otoxin of 11 human strains of C.jejuniwere detected in NIH mice inoculatedwith the C. jejuni strains; the methods ofplate immunological hemolysin test andSPA-coagglutination test were employed.Ten strains of the bacteria invaded theingestine; 7 strains (45.46％) were po-sitive in SPA-coagglutination test;and4(36. 36％) produced enterotoxin. C. jejuni inChengdu area possess multiple pathogeni-city, e. g invasivenessand heat--labile entero-toxin,but we did not find definitive corre-lations between the clinical manifestationand resource of strains.
出处
《华西医科大学学报》
CSCD
1990年第4期427-429,共3页
Journal of West China University of Medical Sciences
关键词
空肠弯曲菌
致病机理
肠毒素
Campylobacter jejuni
Pathogenesis
Invasiveness
Enterotoxin
