摘要
肠神经胶质细胞除了对神经支持功能外,可能还具有许多复杂的内平衡调控功能。例如对肠屏障功能和内稳态的调节,神经周边内环境和肠动力内平衡的调节,钙平衡及离子平衡的调节,神经介质功能和免疫功能的调节。维持了肠神经系统的完整性。最近发现,肠神经胶质细胞在消化道疾病的发生、发展中有重要作用。这一领域的研究将为大家提供重新认识这些疾病的窗口,有助于相关消化道疾病的预防和治疗。
The role of enteric glial cells（EGCs） maybe have many complicatedregulatory function of homeostasis besides its function of nervous surporting, for example, the regulation of intestinal ban＇ier function and homeotasis ,the regulation of. perineuronal homeostasis and gut motility homeostasis,so do the calcium homeostasis and ion homeostasis, neurotransmitter functions and immunological functions. EGCs are essential for maintaining the integrity of ENS. Recent evidence has shown these cells may be involved in the pathophysiological aspects of some gastrointestinal diseases, which provide us with a new field of vision to understand these disease.
出处
《医学综述》
2008年第19期2904-2907,共4页
Medical Recapitulate
关键词
肠神经系统
肠胶质细胞
肠黏膜屏障
内稳定
炎性肠病
Enteric nervous system
Enteric glia ceils
Enteric mucoal barrier
Homeostasis
Inflammatory bowel disease
