摘要
目的评价苯巴比妥钠介入99mTc-EHIDA肝胆显像诊断先天性胆道闭锁(BA)的临床价值。方法应用SPECT仪器对58例临床上持续黄疸的婴儿服用苯巴比妥钠,5mg·kg-1.d-1体重,分两次服用,连续一周后行99mTc-EHIDA肝胆显像,并经手术、病理诊断及随访确诊。结果SPECT诊断为BA29例,经临床确诊为BA24例,婴儿肝炎综合征(IHS)5例;SPECT诊断为IHS29例,均经临床随访确诊。SPECT诊断BA的灵敏度为100%,特异性85.3%,准确度91.4%。结论苯巴比妥钠联合99mTc-EHIDA肝胆显像是一种无创、安全、诊断效能高的检查方法,有助于明确病因,预测治疗效果,对于BA的诊断有较高的临床价值。
Objective Evaluate the diagnostic value of ^99mTc-EHIDA hepatobiliary scintigraphy with Phenobarbitol Sodium in congential biliary atresia（BA）.Methods Fifty-eight infants with consistent jaundice took Phenobarbitol Sodium（5 mg·kg^-1·d^-1 weight,bid ×7d）,then received ^99mTc-EHIDA hepatobiliary scintigraphy with SPECT instrument,the results of all patients were proved by pathology and clinical follow up results.Results Twenty-nine infants were diagnosed as BA by SPECT.Twenty-four of 29 infants were proved BA and 5 of 29 infants were proved infantile hepatitis syndrome（IHS）;29 infants were diagnosed as IHS by SPECT,and all 29 IHS infants were proved.The sensitivity,specificity and correctrate of this method were 100%,85.3% and 91.4%.Conclusion ^99mTc-EHIDA hepatobiliary scintigraphy with Phenobarbitol Sodium is an anoninvasive,safety,valuable examing method.It will help us definite the etilogy,predict the therapeutic efficacy,and have high clinical value in the diagnosis of BA.
出处
《中国医学影像技术》
CSCD
北大核心
2008年第8期1261-1263,共3页
Chinese Journal of Medical Imaging Technology
