摘要
目的探讨环磷腺苷葡胺和低分子肝素治疗肺源性心脏病急性加重期治疗效果。方法将67例肺源性心脏病急性加重期患者随机分成2组,对照组(33例)给予吸氧、抗生素、平喘、扩血管及利尿等常规治疗;治疗组(34例)在常规治疗的基础上加用环磷腺苷葡胺120mg加入5%葡萄糖溶液250ml静脉滴注,1次/d;低分子肝素2500U,皮下注射,12h/次。疗程共7d。治疗前后进行心功能分级评估、血气分析和心脏超声检查。结果治疗组患者心功能、血气分析和各项心脏指数较对照组改善更为显著(P<0.01)。结论环磷腺苷葡胺和低分子肝素对急性加重期肺源性心脏病患者疗效显著。
Objective To survey the therapeutic effect on patients with cot pulmonale at acute deterio- ration stage by meglumine adenosion eyclophosphate and low moleeular weight heparin. Methods 67 cases with eor pulmonale at acute deterioration stage were randomly divided into two groups. Patients in the control group （ 33 eases） were treated with routine treatment including oxygen uptake, antibiotics, antiasthmaties, vasodilators, diuretics, ete. In addition to the routine treatment, patients in the treatment group （34 eases）were treated with 120 mg of meglumine adenosion eyclophosphate injection through intravenous drip once a day and 2500 U of low molecular weight heparin through subcutaneous injeetion twice a day for 7 days. We observed the ehanges of car- diae function, pulmonary artery pressure （PAP） ,left ventrieular ejection fraction （LVEF）and analysis of the gases in blood before and after the treatment. Results Patients in the treatment group had more significant improvements in heart function and the gases in blood than those in the control group（ P 〈 0. 01 ）. Conclusion Meglumine adenosion cyclophosphate and low molecular weight heparin are significantly effective to treat cor pulmonale at acute deterioration stage.
出处
《中国实用医药》
2008年第26期23-24,共2页
China Practical Medicine
关键词
肺源性心脏病
急性加重期
环磷腺苷葡胺
低分子肝素
Cor pulmonale
Acute deterioration stage
Meglumine adenosion eyelophosphate
Low mo- lecular weight heparin
