摘要
目的：探讨新鲜冰冻血浆融化后24 h内凝血因子的变化,为指导临床治疗提供理论依据。方法：采用ACL 8000自动血凝分析仪对20份血浆样品进行融化后0、6、12、24 h分别测定FIB、FⅦ、FⅧ、FⅨ活性水平。结果：新鲜血浆融化后24 h之内无明显改变的有FIB（P〉0.05）;其他指标在不同时间段各有明显的改变,同时显示FⅧ半衰期为12-24 h。结论：新鲜冰冻血浆融化后放置会有凝血因子活性的衰减,为保证输血质量,尽可能融化后立即输注。
Objective：To explore the changes of coagulation factor activity in warming fresh frozen plasma at different times in order to provide theory basis for clinical transfusion.Methods：A total of 20 samples of FFP were investigated.FIB,FⅦ,FⅧ,FⅨ were detected at 0,6,12,24 h.Results：FIB was not obviously changed（P〉0.05） for 24 h after warming,but the others were obviously changes（P〈0.05） at different time phases.The half-life of FⅧ was 12-24 h.Conclusion：Coagulation factor activity decreases of FFP after warming.In order to improve quality of transfusion,it had better to be transfused immediately after warming.
出处
《中国卫生检验杂志》
CAS
2008年第9期1825-1826,共2页
Chinese Journal of Health Laboratory Technology
