摘要
[目的]探讨年龄≤35岁年轻宫颈癌发病相关因素、临床病理特点等。[方法]回顾分析1999￣2007年年龄≤35岁年轻宫颈癌患者58例,并与>35岁中老年组269例临床资料进行对比分析。[结果]年轻宫颈癌组中临床分期原位癌占17.24%,Ⅰ期占53.45%,两者共占70.69%。年轻组中临床表现主要为接触性阴道出血(63.79%,37/58)。发现脉管内癌栓者占34.78%(16/46),发现盆腔淋巴结转移者占32.61%(15/46),与中老年宫颈癌组比较均有显著性差异(P<0.05)。年轻组和中老年组在组织病理学类型、组织学分级、宫颈形态、癌灶大小及宫颈肌层浸润深度方面无差异。[结论]年轻宫颈癌临床分期以早期癌为主,盆腔淋巴结转移率和脉管浸润程度高于中老年宫颈癌组。应重视宫颈癌疾病预防知识的教育及年轻女性的宫颈筛查。
[Purpose] To explore the etiological factors and clinicopathological features in young patients with cervical carcinoma （≤35 years old）. [Methodsl The clinical information of 58 young patients with cervical carcinoma under 35 years old from 1999 to 2007 were retrospectively ana- lyzed and compared to 269 patients over 35 years old. [Results] In young patients group cervical carcinoma in situ accounted for 17.24%, and stage I , 53.45% （both, 70.69%）. Contact bleeding was the main symptom occurred in 63.79% （37/58） of young patients. The rates of the lymph vascular involvement and the pelvic lymph metastasis were 34.78% （16/46）and 32.61% （15/46） in young patients group respectively, those were Significantly higher than those in elderly patients group（P〈0.05）. There was no significant difference between the young group and the elderly group in stage, grade, histologic type, size of the cervical tumor and the depth of tumor invasion. [Conclusions] Early stage is accounts for greater number in young patients with cervical carcinoma. The rates of the pelvic lymph metastasis and lymph vascular involvement in young patients are higher than those in elderly patients with cervical carcinoma. The preventional education for cervi- cal cancer and cervical screening to voung women should be highlighted.
出处
《肿瘤学杂志》
CAS
2008年第9期715-718,共4页
Journal of Chinese Oncology
关键词
宫颈肿瘤
病理学
青年人
病例对照研究
cervical neoplasms
pathology
younger
case control studies
