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应用Amplatzer血管塞封堵动脉导管未闭及初步疗效评价 被引量:6

Transcatheter Closure of Patent Ductus Arteriosus by Amplatzer Vasucular Plug With the Priliminary Effect Evaluation
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摘要 目的:应用 Amplatzer 血管塞封堵动脉导管未闭(PDA)并对其疗效进行评价。方法:全组共11例,年龄4.0~17.0(10.09±5.17)岁,体重15~63(35.05±16.20)kg。PDA 长度为8.4~20.9(14.09±3.50)mm,最狭窄处均位于肺动脉侧,直径为1.0~2.0(1.48±0.35)mm;经导管置入 Amplatzer 血管塞封堵PDA。封堵后5~10 min 行胸主动脉造影评价疗效,术后24 h、1个月、3个月及1年进行随访观察有无残余分流及再通。结果:全组技术成功率为100%,无任何并发症。术后10 min 胸主动脉造影示11例动脉导管均完全闭合,无残余分流;5例完成1年随访,PDA 完全闭合,未见再通。结论:应用 Amplatzer 血管寨封堵类似于长管状的 PDA 是一种安全、有效的非手术方法,技术成功率高,即刻效果好,近、中远期随访疗效可靠。 Objective :To conduct transcatheter closure of patent ductus arteriosus (PDA) by Amplatzer vascular plug and to preliminarily evaluate the safety and effect of the treatment. Methods : A total of 11 PDA patients with the mean age of 10. 09 ± 5. 17 years ( ranging from 4. 0 to 17.0 years) and the mean body weight of 35.05 ± 16.20 kg( ranging from 15 to 63 kg)were occluded by Amplatzer vascular plug. The length of PDA were 8.4 - 20. 9 ( 14. 09 ± 3. 50) mm, the most narrow spots were at the side of pulmonary artery with the diameter of 1.0 - 2.0 ( 1.48 ± 0. 35 ) mm. Aortography was performed to evaluate the effect of 5-10 minutes after the procedure. Echocardiography was performed at 24 hours,one month,three months and 1 year after the closure to examine whether there was residual shunt and recanalization. Results:The technical successful rate was 100% without complications. Aortography revealed there were complete occlusion without residual shunt in all 1 lcases at 10 minutes after the procedure. One year follow up was done in 5 patients and no residual shunt observed. Conclusion :Transcatheter closure of PDA with Amplatzer vascular plug was a safe and effective method ,it has the high successful rate with the complete closure immediately after the procedure ;the short and mid-term follow-up showed a good result as well.
出处 《中国循环杂志》 CSCD 北大核心 2008年第4期260-262,共3页 Chinese Circulation Journal
关键词 动脉导管未闭 介入治疗 Amplatzer血管塞 Patent ductus arteriosus Trascatheter closure Amplatzer plug
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参考文献9

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同被引文献45

  • 1蒋世良,黄连军,徐仲英,赵世华,凌坚,郑宏,张戈军,张岩,戴汝平,刘延玲,王云.先天性心脏病介入治疗的严重并发症分析及其防治[J].中国循环杂志,2005,20(1):21-24. 被引量:100
  • 2李奋,周爱卿,蒋世良,李渝芬,韩玲,朱鲜阳,孔祥清,王广义,马沛然,张玉顺,华益民.动脉导管未闭封堵的临床研究[J].临床儿科杂志,2006,24(11):924-926. 被引量:37
  • 3Gross RE, Hubbard JP. Surgical ligation of a patent ductsu arteriosus : a report of first successful case. JAMA, 1939,112 : 729-931.
  • 4Krichenko A, Benson LN. Burrows P, et al. Angiographic classification of the isolated, persistently patent ductus arteriosus and implications for percutaneous catheter occlusion. Am J Cardiol, 1989, 63: 877.
  • 5Porstmann W, Wiemy L, Warnke H. The closure of the patent ductus arteriosus without thinactomy. Thoraxchir Vask Chir, 1967,15:199-203.
  • 6Rashkind W J, Mullins CE, Hellenbrand WH, et al. Nonsurgieal closure of patent duetus arteriosus: clinical application of the rashkind PDA oceluder system. Circulation, 1987,75:583-592.
  • 7Cambier PA, Kirby WC, Moore JW. Percutaneous closure of the small less tban 2.5 mm) patent ductus arteriosus using coil embolization. Am J Cardiol, 1992,69:815-816.
  • 8Masura J, Walsh KP, Thanopoulous B, et al. Catheter closure of moderate-to large-sized patent ductus arteriosus using the new Amplatzer duct occluder: Immediate and short-term results. J Am Coll Cardiol, 1998,31 : 878-882.
  • 9Hoyer MH. Novel use of the Amplatzer Plug for closure of a patent duetus arteriosus. Catheter Cardiovasc Interv, 2005,65:577- 580.
  • 10Podnar T, Masura J. Transcatheter occlusion of residual patent ductus arteriosus after surgical ligation. Pediatr Cardiol, 1999, 20: 126-130.

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