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白血病治疗新靶点——白血病干细胞 被引量：2

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作者 陈运贤 丁倩
机构地区 中山大学附属第一医院血液科
出处 《新医学》 北大核心 2008年第9期613-614,共2页 Journal of New Medicine
基金 广东省科技计划项目(2007B031516009)
关键词 白血病 干细胞 靶向治疗 单克隆性异质性疾病
分类号 R733.7 [医药卫生—肿瘤]
  • 相关文献

参考文献7

  • 1孟凡义.慢性粒细胞白血病的治疗[J].新医学,2004,35(7):392-393. 被引量：10
  • 2张国材,罗绍凯,李娟,彭爱华,童秀珍,郑冬,谭恩勋,洪文德.异基因外周血干细胞与异基因骨髓移植治疗白血病疗效的比较[J].中山大学学报（医学科学版）,2003,24(2):171-174. 被引量：3
  • 3GUAN Y, GERHARD B, HOGGED E. Detection, isolation, and stimulation of quiescent primitive leukemic progenitor cells from patients with acute myeloid leukemia (AML) [J]. Blood, 2003, 101 (8) : 3142-3149.
  • 4LEVIS M, MURPHY K M, PHAM R, et al. Internal tandem duplications of the FLT3 gene are present in leukemia stem cells [ J ]. Blood, 2005, 106 (2) : 673-680.
  • 5GUTHRIDGE M A, BARRY E F, FELQUER FA, et al. The phosphoserine-585-dependent pathway of the GM-CSF/IL-3/IL-5 receptors mediates hematopoietic cell survival through activation of NF-κB and induction of bcl- 2[J]. Blood, 2004, 103 (3): 820-827.
  • 6XU Q, SIMPSON S E, SCIALLA T J, et al. Survivial of acute myeloid leukemia cells requires PI3 kinase activation [ J ]. Blood, 2003, 102 ( 8 ) : 972-980.
  • 7PENG C, BRABIN J, HU Y, et al. Inhibition of heat shock protein 90 prolongs survival of mice with BCR-ABL-T315I-induced leukemia and suppresses leukemic stem cells[J]. Blood, 2007, 110 (2) : 678-685.

共引文献11

同被引文献30

  • 1苗恒,陶勇,黎晓新.重视眼部移植物抗宿主病的诊断和治疗[J].中华眼科医学杂志（电子版）,2014,4(1):1-6. 被引量：7
  • 2黄珠,顾扬顺.慢性移植物抗宿主病的干眼症的研究新进展[J].国际眼科纵览,2006,30(6):401-404. 被引量：4
  • 3So CW, Karsunky H, Passegue E, et al. MLL - GAS7 transforms multipotent hematopoietic progenitors and induces mixed lineage leukemias in mice[J]. Cancer Cell ,2003,3(2) :161 -171.
  • 4Huntly B J, Shigematsu H, Deguchi K, et al. MOZ - TIF2, but not BCR- ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors [ J]. Cancer Cell, 2004,6 (6) :587 -596.
  • 5Krivtsov AV, Twomey D, Feng Z, et al. Transformation from committed progenitor to leukaemia stem cell initiated by MLL - AF9 [ J]. Nature. 2006,442(7104) :818 - 822.
  • 6Chen W,Kumar AR, Hudson WA, et al. Malignant transformation initiated by Mll-AF9: gene dosage and critical target cells [J]. Cancer Cell, 2008,13 (5) :432 - 440 .
  • 7Guzman ML, Neering SJ, Upchurch D, etal. Nuclear factor- kappa B is constitutively activated in primitive human acute myelogenous leukemia ceils [J]. Blood, 2001,98 (8) :2301 -2307.
  • 8Guan Y, Gerhard B, Hogge DE. Detection, isolation, and stimu- lation of quiescent primitive leukemic progenitor cells from patients with acute myeloid leukemia (AML) [ J]. Blood, 2003, 101 (8) :3142 -3149 .
  • 9Ravandi F, Estrov Z. Eradication of leukemia stem cells as a new goal of therapy in leukemia [J]. Clin Cancer Res, 2006,12 (2) : 340 - 344.
  • 10Gillet JP, Efferth T, Steinbach D, et al. Microarray - based detection of multidrug resistance in human tumor cells by expression profiling of ATP- binding cassette transporter genes [ J ]. Cancer Res,2004, 64 (24) : 8987 - 8993.

引证文献2

二级引证文献18

新医学
2008年 第9期

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