摘要
目的：研究微创穿刺术治疗高血压脑出血的最佳时机。方法：41例高血压脑出血随机分为4组，即手术距发病时间〈6h组、6～12h组、12～18h组和18～24h组；用再出血率、近期疗效、远期疗效、病死率、转归优良率等疗效评价指标进行组间比较。结果：再出血等并发症发生率无显著差异；3个月时的临床转归优良率：〈6h组〉6～12h组和12～18h组〉18～24h组（P〈0．05），18～24h组病死牢最高，达30％（3／10）。结论：高血压脑出血发病后6h内是微创穿刺术治疗的最佳时机。
Objective： To study the best oppommity for minimal invasive puncture in the treatment of hypertensive intracerebral hemorrhage. Methods： Forty-one patients with hypertensive intracerebral hemorrhage were randomly divided into four groups： 〈6 h, 6-12 h, 12-18 h and 18-24 h from the onset of symptoms. The comparison among groups in outcome measures were performed, including the rebleeding rate, short-term efficacy, long-term efficacy, mortality, and excellent and good rate. Results： The incidence of complication such as rebleeding etc had no significantly difference in the four groups. The excellent and good rates of clinical outcomes at 3 months were the 〈6 h group 〉6-12 h group, and 12-18 h group 〉 18-24 h group （P 〈 0.05）. The 18-24 h group had the highest mortality （30%, 3/10）. Conclusions： Within 6 h after the onset of hypertensive intracerebral hemorrhage was the best opportunity for the minimal invasive puncture.
出处
《国际脑血管病杂志》
2008年第8期565-570,共6页
International Journal of Cerebrovascular Diseases
基金
国家“十五”科技攻关计划基金资助项目（No.2001BA703B16）,国家“十一五”科技支撑计划基金资助项目（No.2006BAI01A13）,卫生部科学研究基金资助项目（No.wsbkyjj2002-02-008）
关键词
脑出血
高血压
穿刺术
手术时机
intracerebral hemorrhage
hypertension
puncture
operative timing
