摘要
目的观察体外循环(CPB)心脏手术前后血清/浆甲状腺激素(TH)的变化规律,探讨CPB心脏手术对甲状腺功能的影响及其临床意义。方法运用微粒子酶免疫分析方法和荧光偏振免疫分析法测定34例CPB心脏手术患者术前、术后总甲状腺素(TT4)、总三碘甲状腺原氨酸(TT3)、游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、促甲状腺激素(TSH)的水平。结果CPB心脏手术后TT3、FT3明显减低,TT4、FT4减低或在正常范围内,TSH减低或正常。结论CPB心脏手术可引起TH水平变化,表现为低T3综合征,其对术后心功能恢复产生一定的影响。
Objective To observe the changes of thyroid hormone（TH） level before and after cardiac surgery under cardiopulmonary bypass （CPB） and study the effect on thyroid. Methods The concentration of serum TH and thyroidstimulating hormone（TSH） were determined by microparticle enzyme immunoassay and fluorescence polarisation immunoassay in 34 patients before and after cardiac surgery under CPB. Results After cardiac surgery under CPB, total triiodothyronine （TT3） and free triiodothyronine （FT3） decreased, total tetraiodothyronine （TT4） and free tetraiodothyronine （FT4） decreased or were in normal range, and TSH decreased or was in normal range. Conclusions Cardiac surgery under. CPB has effect on the TH level, associated with low T3 syndrome and it also influences the recovery of cardiac function after operation.
出处
《检验医学》
CAS
北大核心
2008年第5期469-471,共3页
Laboratory Medicine
