摘要
类固醇激素合成急性调节蛋白(StAR)在胆固醇的代谢中发挥重要的作用。近期研究表明StAR同样表达于肝脏组织中,通过调节胆汁酸的合成,增加胆固醇的排泄。这为脂肪肝等脂类代谢异常类疾病的防治提供了一条新的途径。
Steroidogenic acute regulatory protein plays a role in cholesterol metabolism. Recently, researches indicate that it is also expressed in the liver. StAR increases the excretion of cholesterol by regulating the synthesis of bile acid. The findings provide a new way for the prevention and cure of diseases of lipid dysfunction such as hepar adiposum.
出处
《国际病理科学与临床杂志》
CAS
2008年第4期358-361,共4页
Journal of International Pathology and Clinical Medicine
关键词
类固醇激素合成急性调节蛋白
胆汁酸合成
胆固醇转运
steroidogenic acute regulatory protein（STAR）
synthesis of bile acid
cholester-ol transport
